Results 101 to 110 of about 1,265,582 (308)

RAMP3 deficiency enhances postmenopausal obesity and metabolic disorders

Peptides, 2018
There is a marked increase in the incidence of visceral adiposity and insulin resistance among women following menopause. Adrenomedullin (AM) is an endogenous peptide first identified as a vasodilator, but now known to exert a variety of physiological effects.
Teng, Liu, Akiko, Kamiyoshi, Megumu, Tanaka, Shiho, Iida, Takayuki, Sakurai, Yuka, Ichikawa-Shindo, Hisaka, Kawate, Kazutaka, Hirabayashi, Kun, Dai, Nanqi, Cui, Masaaki, Tanaka, Yangxuan, Wei, Keisei, Nakamura, Shuhei, Matsui, Akihiro, Yamauchi, Takayuki, Shindo   +15 more
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-frequency electromagnetic radiation promoted hepatic lipid metabolism via the adiponectin pathway in mice

Ecotoxicology and Environmental Safety
Radiofrequency electromagnetic radiation (RF-EMR) is ubiquitous in daily life, and the complexity of the electromagnetic environment continues to increase. Nevertheless, research on the biological effects of compound radiofrequency radiation—particularly
Jing Xu, Xinyu Wang, Menghua Li, Lihui Zhang, Xuelong Zhao, Guofu Dong, Changzhen Wang   +6 more
doaj   +1 more source

The Photorespiratory BOU Gene Mutation Alters Sulfur Assimilation and Its Crosstalk With Carbon and Nitrogen Metabolism in Arabidopsis thaliana

Frontiers in Plant Science, 2018
This study was aimed at elucidating the significance of photorespiratory serine (Ser) production for cysteine (Cys) biosynthesis. For this purpose, sulfur (S) metabolism and its crosstalk with nitrogen (N) and carbon (C) metabolism were analyzed in ...
Sladjana Samuilov, Dominik Brilhaus, Nadine Rademacher, Samantha Flachbart, Leila Arab, Saleh Alfarraj, Franziska Kuhnert, Stanislav Kopriva, Andreas P. M. Weber, Tabea Mettler-Altmann, Heinz Rennenberg, Heinz Rennenberg   +11 more
doaj   +1 more source

ALS gene overexpression and enhanced metabolism conferring Digitaria sanguinalis resistance to nicosulfuron in China. [PDF]

Front Plant Sci, 2023
Wang R, Sun Y, Lan Y, Wei S, Huang H, Li X, Huang Z.   +6 more
europepmc   +1 more source

Consortium Building For PEM MFC Using Synthetic Media As Substrate [PDF]

, 2011
Microbial production of electricity is an important form of bioenergy since Microbial Fuel cells (MFC) offer the possibility of extracting electric current from a wide range of organic wastes and renewable biomass.
Arti Yadav, Dimpal Parida, Muralidharan Ayyappan, Ramya Mohandass   +3 more
core   +1 more source

Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]

, 2011
The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E., Metzler-Zebeli, B.U., Mosenthin, R., Verstegen, M.W.A.   +3 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Cytochrome P450s-Involved Enhanced Metabolism Contributes to the High Level of Nicosulfuron Resistance in Digitaria sanguinalis from China. [PDF]

Biology (Basel), 2023
Wang X, Hu W, Li Y, Jiang M, Zhao N, Cao H, Liao M.   +6 more
europepmc   +1 more source

Dynamic energy budget approach to evaluate antibiotic effects on biofilms [PDF]

, 2017
Quantifying the action of antibiotics on biofilms is essential to devise therapies against chronic infections. Biofilms are bacterial communities attached to moist surfaces, sheltered from external aggressions by a polymeric matrix.
Birnir, Bjorn, Carpio, Ana, Cebrian, Elena, Vidal, Perfecto   +3 more
core   +3 more sources