Results 41 to 50 of about 104,369 (254)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Ephemeral Node Identifiers for Enhanced Flow Privacy

Future Internet
The Internet Protocol (IP) uses numerical address values carried in IP packets at the network layer to allow correct forwarding of packets between source and destination. Those address values must be kept visible in all parts of the network.
Gregor Tamati Haywood, Saleem Noel Bhatti   +1 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Address Privacy of Bluetooth Low Energy

Mathematics, 2022
Bluetooth low energy (LE) devices have been widely used in the Internet of Things (IoT) and wireless personal area networks (WPAN). However, attackers may compromise user privacy by tracking the addresses of the LE device. The resolvable private address (
Dazhi Sun, Yangguang Tian
doaj   +1 more source

Privacy enhancing primitives [PDF]

, 2023
Nowadays, cryptography is ubiquitous in people’s daily interactions. Secure messaging apps implement end-to-end encrypted communication channels between individuals, web browsers encrypt their client-to-server communication, physical access control systems use hardware security devices, and many more.
openaire   +1 more source

Enhancing Speech Privacy with Slicing

Interspeech 2022, 2022
Privacy preservation calls for speech anonymization methods which hide the speaker's identity while minimizing the impact on downstream tasks such as automatic speech recognition (ASR) training or decoding. In the recent VoicePrivacy 2020 Challenge, several anonymization methods have been proposed to transform speech utterances in a way that preserves ...
Maouche, Mohamed, Srivastava, Brij Mohan Lal, Vauquier, Nathalie, Bellet, Aurélien, Tommasi, Marc, Vincent, Emmanuel   +5 more
openaire   +3 more sources

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Preserving Patient's Anonymity for Mobile Healthcare System in IoT Environment

International Journal of Distributed Sensor Networks, 2016
Emerging IoT (Internet of Things) technologies provide many benefits to the improvement of healthcare service. The successful deployment of IoT depends on ensuring security and privacy that need to adapt to their processing capabilities.
Seungsoo Baek, Seung-Hyun Seo, Seungjoo Kim   +2 more
doaj   +1 more source