Results 101 to 110 of about 337,682 (315)

mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. [PDF]

, 2018
Metabotropic glutamate receptor 5 (mGluR5) antagonism inhibits cocaine self-administration and reinstatement of drug-seeking behavior. However, the cellular and molecular mechanisms underlying this action are poorly understood.
Bi, Guo-Hua, Gardner, Eliot L, He, Yi, Jordan, Chloe J, Li, Jie, Li, Xia, Peng, Xiao-Qing, Xi, Zheng-Xiong, Yang, Hong-Ju, Zhang, Hai-Ying   +9 more
core   +2 more sources

Pancreatic cancer mortality trends attributable to high fasting blood sugar over the period 1990–2019 and projections up to 2040

Frontiers in Endocrinology
BackgroundPancreatic cancer (PC) is a prevalent malignancy within the digestive system, with diabetes recognized as one of its well-established risk factors.MethodsData on PC mortality attributed to high fasting blood sugar were retrieved from the Global
Yongguang Wei, Yongguang Wei, Yongguang Wei, Zedong Qin, Xiwen Liao, Xiwen Liao, Xiwen Liao, Xin Zhou, Xin Zhou, Xin Zhou, Huasheng Huang, Huasheng Huang, Huasheng Huang, Chenlu Lan, Chenlu Lan, Chenlu Lan, Wei Qin, Wei Qin, Wei Qin, Guangzhi Zhu, Guangzhi Zhu, Guangzhi Zhu, Hao Su, Hao Su, Hao Su, Tao Peng, Tao Peng, Tao Peng   +27 more
doaj   +1 more source

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

Advanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer, Joanna M. Sadowska, Nadia Roumans, Christian Plank, Christopher H. Evans, Fergal J. O'Brien, Martijn van Griensven, Elizabeth R. Balmayor   +7 more
wiley   +1 more source

Clinical trial: multicentral preventive antibiotics with cystectomy within enhanced recovery after surgery (MACS)

, 2023
М. В. Беркут, E. M. Mamizhev, Tatiana Yu. Galunova, A.V. Novik Novik, Дарья Игоревна Румянцева, Александр Константинович Носов   +5 more
openalex   +2 more sources

Impact of Tailored-Enhanced Recovery After Surgery Versus Conventional Care in Patients of Gastro-Duodenal Perforation: A Pilot Randomized Control Trial [PDF]

, 2023
Cherring Tandup, Abhinav Chauhan, Rajeev Chauhan, Vipul Thakur, Swapnesh Sahu, Lileswar Kaman, Siddhant Khare, Yashwant Sakaray, Krishna N Nenavath, Kailash Chand Kurdia   +9 more
openalex   +1 more source

Aptamer Functionalized Hydrogel Dressings for Post‐Surgery Tumor Recurrence Inhibition and Tissue Reconstruction

Advanced Functional Materials, EarlyView.
Post‐surgical tumor therapy struggles with recurrence and inefficient healing. Anti‐tumor DNA aptamer functionalized gelatin hydrogels, Apt‐GelMA, simultaneously address both issues by suppressing tumor regrowth via targeted tumor cell inhibition and enhancing wound healing through improved cell adhesion and migration. Their biocompatibility, stability,
Tianyue Li, Xin‐Yi Qian, Zi‐Yuan Li, Hao‐Wen Li, Poh‐Ching Tan, Chenghuizi Hu, Jiajun Jin, Shuang‐Bai Zhou, Qing‐Feng Li, He Tian, Junji Zhang, Itamar Willner   +11 more
wiley   +1 more source

Feasibility research of enhanced recovery after surgery implemented in esophageal cancer patients who underwent neoadjuvant chemotherapy [PDF]

, 2022
Zhanpeng Tang, Xirui Zhu, Yanzhi Li, Chenghao Qu, Lin Li, Shuhai Li, Lei Qi, Ming Lü, Chuanle Cheng, Hui Tian   +9 more
openalex   +1 more source

S-allylcysteine Improves Blood Flow Recovery and Prevents Ischemic Injury by Augmenting Neovasculogenesis. [PDF]

, 2017
Studies suggest that a low level of circulating human endothelial progenitor cells (EPCs) is a risk factor for ischemic injury and coronary artery disease (CAD). Consumption of S-allylcysteine (SAC) is known to prevent CAD.
Chao, Che-Yi, Chiang, En-Pei Isabel, Chiu, Shao-Chih, Rodriguez, Raymond L, Syu, Jia-Ning, Tang, Feng-Yao, Tsai, Shu-Yao, Yang, Mei-Due   +7 more
core   +1 more source

The prognostic value of preoperative D-dimer to albumin ratio for overall survival and progression-free survival in colorectal cancer

Frontiers in Physiology
Introduction: This study aimed to explore the predictive value of the D-dimer-to-albumin ratio (DAR) for progression-free survival (PFS) and overall survival (OS) in patients with colorectal cancer (CRC).Methods: The Kaplan-Meier method was used to plot ...
Lishuang Wei, Hailun Xie, Hailun Xie, Qiwen Wang, Qiwen Wang, Shuangyi Tang, Jialiang Gan, Jialiang Gan   +7 more
doaj   +1 more source

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

Advanced Functional Materials, EarlyView.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño, Carlos Bendicho‐Lavilla, Haya Alfassam, Bárbara Blanco‐Fernández, Abdul W. Basit, Francisco J. Otero‐Espinar   +5 more
wiley   +1 more source