Results 101 to 110 of about 479,483 (399)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Preface to enhanced recovery after surgery [PDF]

Journal of Thoracic Disease, 2018
Often prefaces make you want to continue reading the book you would like to introduce as a mitral rite, but this does not depend (fortunately) on the preface. To avoid such unpleasant problems, in the dialogues with Leucos, Cesare Pavese himself wrote the preface expressing himself in a third person.
openaire   +3 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Enhanced recovery after surgery [PDF]

, 2012
The Enhanced Recovery After Surgery model of perioperative care targets the obstacles to recovery following major abdominal surgery: pain, gastrointestinal dysfunction and immobility.
Hendry, Paul
core   +1 more source

Risk factors for gastric cancer: an umbrella review of systematic reviews and meta-analyses

Frontiers in Oncology
BackgroundThis umbrella review aims to critically appraise and synthesize epidemiological evidence from meta-analyses to identify and classify risk and protective factors associated with gastric cancer.MethodsPubMed, Embase, Web of Science, and the ...
Jin Long Liang, Jin Long Liang, Jin Long Liang, Jin Long Liang, Hui Ming Yuan, Hui Ming Yuan, Hui Ming Yuan, Hui Ming Yuan, Chao Quan, Chao Quan, Jun Qiang Chen, Jun Qiang Chen, Jun Qiang Chen, Jun Qiang Chen   +13 more
doaj   +1 more source

3D MRI Tract‐Specific Spinal Cord Lesion Pattern Improves Prediction of Distinct Neurological Recovery

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To distinguish lateralized motor‐ and sensory‐tract damage after acute spinal cord injury (SCI) and explore its predictive power for motor and sensory recovery. Methods Thirty‐five SCI patients (two female) from a multi‐center data set (placebo‐arm of the Nogo‐A‐Inhibition in SCI trial) underwent routine T2‐weighted sagittal MRI ...
Lynn Farner, Tim M. Emmenegger, Simon Schading‐Sassenhausen, Julia Berroth, Maryam Seif, Armin Curt, Patrick Freund, The Nogo Inhibition in Spinal Cord Injury Study Group   +7 more
wiley   +1 more source

Assessing the Value of Prehabilitation in Patients Undergoing Colorectal Surgery According to the Enhanced Recovery After Surgery (ERAS) Pathway for the Improvement of Postoperative Outcomes: Protocol for a Randomized Controlled Trial [PDF]

, 2017
A key element in the postoperative phase of the standardized Enhanced Recovery After Surgery (ERAS) treatment pathways is mobilization. Currently, there are no recommendations in the ERAS guidelines for preoperative physical activity. Patients undergoing
Breitenstein, Stefan, Gisi, David, Gloor, Severin, Greco, Nicola, Kerstan-Huber, Marta, Merki-Künzli, Cornelia, Misirlic, Merima, Mungo, Giuseppe, Raptis, Dimitri Aristotle, Switalla, Denise, Tschuor, Christoph, Wirz, Markus   +11 more
core   +1 more source

An audit of gynae-oncology practices in ovarian cancer treatment based on enhanced recovery after surgery (ERAS) protocol amongst two gynae-oncology units, in UK and in Pakistan [PDF]

, 2021
Objective: To compare peri-operative practices and complications in ovarian cancer patients undergoing upfront surgery for primary disease under enhanced recovery after surgery protocol and traditional practices.Methods: The retrospective cross-sectional
Ahmed, Amber, Akhtar, Munazza, Aziz, Aliya, Barton, Desmond Pj, Chishti, Uzma   +4 more
core   +2 more sources

Association of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations.
Nina Massad, Lili Zhou, Brian Manolovitz, Negar Asdaghi, Hannah Gardener, Hao Ying, Carolina M. Gutierrez, Angus Jameson, David Rose, Mohan Kottapally, Amedeo Merenda, Kristine O'Phelan, Sebastian Koch, Jose G. Romano, Tatjana Rundek, Ayham Alkhachroum   +15 more
wiley   +1 more source

Enhanced Recovery after Surgery: History, Key Advancements and Developments in Transplant Surgery

Journal of Clinical Medicine, 2021
Enhanced recovery after surgery (ERAS) aims to improve patient outcomes by controlling specific aspects of perioperative care. The concept was introduced in 1997 by Henrik Kehlet, who suggested that while minor changes in perioperative practise have no ...
H. Golder, V. Papalois
semanticscholar   +1 more source