Results 11 to 20 of about 337,682 (315)

Elevation of preoperative serum hs-CRP is an independent risk factor for malnutrition in patients with gastric cancer

open access: yesFrontiers in Oncology, 2023
BackgroundRecent studies have reported hypersensitive C-reactive protein (hs-CRP) linked to clinicopathological characteristics and nutritional status of the tumor, but its clinical significance in GC remains unclear.
Yuantian Mao   +21 more
doaj   +1 more source

Identification of circRNA–miRNA–mRNA networks contributes to explore underlying pathogenesis and therapy strategy of gastric cancer

open access: yesJournal of Translational Medicine, 2021
Background Circular RNAs (circRNAs) are a new class of noncoding RNAs that have gained increased attention in human tumor research. However, the identification and function of circRNAs are largely unknown in the context of gastric cancer (GC). This study
Zhijie Dong   +8 more
doaj   +1 more source

Sodium nitroprusside protects HFD induced gut dysfunction via activating AMPKα/SIRT1 signaling

open access: yesBMC Gastroenterology, 2021
Background Activation of Adenosine 5′-monophosphate-activated protein kinase/Sirtuin1 (AMPK/SIRT1) exerts an effect in alleviating obesity and gut damage. Sodium nitroprusside (SNP), a nitric oxide (NO) donor, has been reported to activate AMPK.
Xiaomei Li   +6 more
doaj   +1 more source

Biomimetic Metal-Organic Framework Nanoparticles for Synergistic Combining of SDT-Chemotherapy Induce Pyroptosis in Gastric Cancer

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
In recent years, sonodynamic therapy (SDT) has been widely developed for cancer research as a promising non-invasive therapeutic strategy. Here, we synthesized zeolitic imidazole frameworks-8 (ZIF-8) and utilized its properties to encapsulate hydrophobic
Zhu Yu   +20 more
doaj   +1 more source

Combination of Geriatric Nutritional Risk Index and Carcinoembryonic Antigen to Predict the Survival of Patients With Colorectal Cancer

open access: yesFrontiers in Nutrition, 2022
BackgroundThis study explored the value of the combination of Geriatric Nutritional Risk Index (GNRI) and carcinoembryonic antigen (CEA) for the prognosis assessment of CRC patients.MethodsThis study retrospectively enrolled 1,014 CRC patients who ...
Hailun Xie   +17 more
doaj   +1 more source

Neutrophil-albumin ratio as a biomarker for postoperative complications and long-term prognosis in patients with colorectal cancer undergoing surgical treatment

open access: yesFrontiers in Nutrition, 2022
BackgroundTo explore the prognostic value of the preoperative neutrophil-albumin ratio (NAR) in patients with colorectal cancer (CRC) undergoing surgical treatment.Materials and methodsThe standardized log-rank statistic was used to determine the optimal
Hailun Xie   +17 more
doaj   +1 more source

Case Report: A case of hepatocellular carcinoma with aberrant right hepatic artery treated with transarterial chemoembolization and infusion chemotherapy separately to bilobar lesion combining with systemic therapies and sequential hepatectomy

open access: yesFrontiers in Oncology, 2023
BackgroundHepatocellular carcinoma (HCC) with a dismal prognosis is the second most deadly malignancy globally. Surgery is believed to be a curative approach. Nevertheless, there is still a considerable probability of postoperative recurrence.
Yong-Guang Wei   +21 more
doaj   +1 more source

High-Fat Diet Affects Heavy Metal Accumulation and Toxicity to Mice Liver and Kidney Probably via Gut Microbiota

open access: yesFrontiers in Microbiology, 2020
Previous studies proved that heavy metals could increase the risk of disease by acting on the gut microbiota. Meanwhile, gut microbiota played important roles in detoxifying heavy metals.
Ting Liu   +12 more
doaj   +1 more source

MiR-29b-3p Inhibits Migration and Invasion of Papillary Thyroid Carcinoma by Downregulating COL1A1 and COL5A1

open access: yesFrontiers in Oncology, 2022
IntroductionMicroRNAs (miRNAs) are small noncoding RNA molecules that regulate genetic expression and are also vital for tumor initiation and development. MiR-29b-3p was found to be involved in regulating various biological processes of tumors, including
Congjun Wang   +18 more
doaj   +1 more source

Prognostic genes in colon cancer and their correlation with immune cells: an analysis based on bioinformatics

open access: yes结直肠肛门外科, 2022
[Objectives] To identify prognostic genes in colon cancer and their correlation with immune cells. [Methods] Differentially expressed genes (DEGs) were screened using the Gene Expression Omnibus (GEO) database.
Gu Zhiwen   +5 more
doaj   +1 more source

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