Results 61 to 70 of about 617,337 (267)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Electrical Conductivity Enhancement and Electronic Applications of 2D Ti3C2Tx MXene Materials

Advanced Materials Interfaces, 2021
In the past 10 years, MXene (transition metal carbides, nitrides, and carbonitrides), a 2D nanomaterial, has become one of the research hotspots with its hydrophilic ends, solution machinability, and excellent electronic, mechanical, and optical ...
Chunyang Qiao, Han Wu, Xiyan Xu, Zhengxin Guan, Wei Ou‐Yang   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Corpus-Based Materials and Learning Non-Congruent Idioms by Iranian EFL Learners: Enhanced and Unenhanced Input [PDF]

Journal of Language Horizons, 2019
The current study aimed at probing the impact of using enhanced and unenhanced corpus-based material on non-congruent idiom learning by Iranian female intermediate EFL learners.
Hoda Estefaei, Alireza Amjadiparvar
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Capacitance enhancement by ion-laminated borophene-like layered materials

Nature Communications
Atomically flat two-dimensional networks of boron are attracting attention as post-graphene materials. An introduction of cations between the boron atomic layers can exhibit unique electronic functions that are not achieved by neutral graphene or its ...
Tetsuya Kambe, Masahiro Katakura, Hinayo Taya, Hirona Nakamura, Takuya Yamashita, Masataka Yoshida, Akiyoshi Kuzume, Kaori Akagami, Ryota Imai, Jumpei Kawaguchi, Shigeyuki Masaoka, Shoichi Kubo, Hiroaki Iino, Atsushi Shishido, Kimihisa Yamamoto   +14 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

THE EFFECT OF MULTIMEDIA-BASED TEACHING MATERIALS IN SCIENCE TOWARD STUDENTS’ COGNITIVE IMPROVEMENT

Jurnal Pendidikan IPA Indonesia, 2016
This study is a meta-analysis study that aimed to determine the effect of multimedia-based teaching materials in science learning to students' cognitive enhancement.
Khoiriah Khoiriah, Tri Jalmo, Abdurrahman Abdurrahman   +2 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source