Results 131 to 140 of about 5,612,960 (265)
Patron-Driven Expedited Cataloging Enhancement to WebPAC Pro
Code4Lib Journal, 2012 This article outlines the development of an integrated patron-driven expedited cataloging feature in the catalog of the Connecticut State University Library System (CONSULS).
Steven Jay Bernstein
doaj
HUMANITY'S END: WHY WE SHOULD REJECT RADICAL ENHANCEMENT
, 2010 Acknowledgments -- 1. What is radical enhancement? -- 2. Radical enhancement and posthumanity -- 3. The technologist: Ray Kurzweil and the law of accelerating returns -- 4. Is uploading ourselves into machines a good bet? -- 5. The therapist: Aubrey
Agar, Nicholas
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
An Investigation to Determine an Optimum Protective Garment Material in Nuclear Medicine
Journal of Biomedical Physics and Engineering, 2018 Aim: The aim of this study is to find an optimum material to protect garment for protection against 99Tcm radionuclide. Materials and Methods: Monte Carlo simulation code was applied to investigate radiation attenuation of 13 shielding materials ...
R Parvaresh +5 more
doaj
Raman enhancement induced by exciton hybridization in molecules and 2D materials
npj 2D Materials and ApplicationsSurface-enhanced Raman spectroscopy (SERS) is a powerful technique for trace-level fingerprinting. Recently, layered two-dimensional (2D) materials have gained significant interest as SERS substrates for providing stable, uniform, and reproducible Raman ...
Hikari Kitadai +3 more
doaj +1 more source
Architecture and materials selection in multi-materials design [PDF]
, 2014 The design process involving both the architecture and the materials represents an hard task mainly due to the high number of potential configurations, thus requiring firstly the development of new and more rigorous approaches but also the development of
BARACCHINI, Paul +6 more
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Enhanced pyroelectric effect through product property and its applications [PDF]
, 2009 Pyroelectric materials have the ability to generate electrical response when they experience a thermal stimulus. This has lead to their deployment in applications such as Infra-Red detectors/sensors, energy harvesting, and ferroelectric electron ...
Chang, Harrison Hoon Seok
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