Results 71 to 80 of about 5,612,960 (265)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Alternative Plasmonic Materials for Fluorescence Enhancement

open access: yesThe Journal of Physical Chemistry C
Noble metals such as gold and silver have been used extensively for a range of plasmonic applications, including enhancing the fluorescence rate of a dye molecule, as evidenced by numerous experiments over the past two decades. Recently, a variety of doped semiconductors have been proposed as alternative plasmonic materials, exhibiting plasmonic ...
Stavros Athanasiou, Olivier J. F. Martin
openaire   +2 more sources

Pressure-induced emission enhancement: A review

open access: yesAPL Materials
The luminescent properties of some materials undergo significant changes under compression. High pressure generated by a diamond anvil cell (DAC) is often used as an external stimulus to explore the relationship between the structures and luminescent ...
Boyu Zou   +7 more
doaj   +1 more source

In-Depth Characterization of bZIP Genes in the Context of Endoplasmic Reticulum (ER) Stress in Brassica campestris ssp. chinensis

open access: yesPlants
Numerous studies have been conducted to investigate the genomic characterization of bZIP genes and their involvement in the cellular response to endoplasmic reticulum (ER) stress.
Aliya Ayaz   +6 more
doaj   +1 more source

THE EFFECT OF MULTIMEDIA-BASED TEACHING MATERIALS IN SCIENCE TOWARD STUDENTS’ COGNITIVE IMPROVEMENT

open access: yesJurnal Pendidikan IPA Indonesia, 2016
This study is a meta-analysis study that aimed to determine the effect of multimedia-based teaching materials in science learning to students' cognitive enhancement.
Khoiriah Khoiriah   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Giant ZT enhancement in rhombohedral GeTe-based thermoelectric materials

open access: yesNature Communications
The peak figure of merit (ZT) of GeTe-based thermoelectric (TE) materials is typically attained in the high-temperature cubic phase, where the inevitable phase transition raises concerns over interfacial instability during operation.
Jincheng Yu   +13 more
doaj   +1 more source

Reflective Inverse Diffusion

open access: yesApplied Sciences, 2016
Phase front modulation was previously used to refocus light after transmission through scattering media. This process has been adapted here to work in reflection.
Kenneth Burgi   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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