Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Purcell enhancement of directional edge photocurrent in a van der Waals self-cavity. [PDF]
Li X +25 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Ultrasensitive Chemical Detection Using Integrating Cavity-Enhanced Raman Spectroscopy. [PDF]
Moore TZ +5 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Contact-Accessible Silver Nanoparticle-Decorated Electrospun Carbon Fibers for Microplastics Detection by SERS. [PDF]
Joshua F +5 more
europepmc +1 more source
Plasmon-Enhanced Raman Sensing with Metal-Insulator-Metal Metasurfaces. [PDF]
Vural Kaymaz S +5 more
europepmc +1 more source
Metal-Enhanced Fluorescence of Nanocomplexes. [PDF]
Yakunin AN +4 more
europepmc +1 more source
Plasmonic electrophosphorescence: "Feeling" blue. [PDF]
Chen Q, Ji S, Chen X, Chen L, Xie G.
europepmc +1 more source
Theoretical Investigation of Stiffness and Vibration Frequency Enhancement in Novel Membrane-Wrapped Lattice Beams. [PDF]
Xi P +5 more
europepmc +1 more source

