Results 211 to 220 of about 617,530 (268)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Dual-Scale Synergistic Design: Oriented Material Stiffness and Deposition Path Planning for Enhanced Performance in Large-Format Additive Manufacturing of Short Carbon Fiber Components. [PDF]

Materials (Basel)
Yang T, Zhao C, Liang J, Li W, Wang C, Zhao Z, Wang K, Gu X.   +7 more
europepmc   +1 more source

RETRACTION: NNK From Tobacco Smoking Enhances Pancreatic Cancer Cell Stemness and Chemoresistance by Creating a β2AR‐Akt Feedback Loop That Activates Autophagy

Molecular Oncology, EarlyView.
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Improved Thermo-Hydraulic Stability and Boiling Heat Transfer Through a Novel Three-Layer Microchannel Heat Sink with 3/4 Open-Ring Pin Fin Arrays. [PDF]

Materials (Basel)
Liu G, Ji C, Liu Z, Lund PD, Liu Y, Xu F, Zhang S, Wang C, Li D.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Contact-Accessible Silver Nanoparticle-Decorated Electrospun Carbon Fibers for Microplastics Detection by SERS. [PDF]

Materials (Basel)
Joshua F, Li Sip YY, Biswas A, Gray V, Chanda D, Zhai L.   +5 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Metal-Enhanced Fluorescence of Nanocomplexes. [PDF]

Materials (Basel)
Yakunin AN, Zarkov SV, Avetisyan YA, Akchurin GG, Tuchin VV.   +4 more
europepmc   +1 more source

Ultrasensitive Chemical Detection Using Integrating Cavity-Enhanced Raman Spectroscopy. [PDF]

Anal Chem
Moore TZ, Bixler JN, Hokr BH, Mason JD, Fry ES, Yakovlev VV.   +5 more
europepmc   +1 more source