Results 341 to 350 of about 8,934,200 (403)

Functional characterization of OXTR-associated enhancers. [PDF]

Hum Mol Genet
Laboy Cintrón D, Sheng RR, Ahituv N.
europepmc   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Current progress and future perspective of super-enhancers: a viable and effective bridge between the transcriptional apparatus and disease. [PDF]

Front Genet
Wang R, Li A, Pang Z.
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Identification of functional non-coding variants associated with orofacial cleft. [PDF]

Nat Commun
Kumari P, Friedman RZ, Curtis SW, Pi L, Paraiso K, Visel A, Rhea L, Dunnwald M, Patni AP, Mar D, Bomsztyk K, Mathieu J, Ruohola-Baker H, Leslie-Clarkson EJ, White MA, Cohen BA, Cornell RA.   +16 more
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Publisher Correction: Combined inhibition of protein kinase B and enhancer of zeste homolog 2: a novel strategy to induce triple-negative breast cancer cell death. [PDF]

Mol Biomed
Zhu X, Wang Y, Zhang L.
europepmc   +1 more source

HBV sequence integrated to enhancer acting as oncogenic driver epigenetically promotes hepatocellular carcinoma development. [PDF]

J Exp Clin Cancer Res
Chen L, Li W, Zai W, Zheng X, Meng X, Yao Q, Li W, Liang Y, Ye M, Zhou K, Liu M, Yang Z, Mao Z, Wei H, Yang S, Shi G, Yuan Z, Yu W.   +17 more
europepmc   +1 more source

Ph+B-ALL is defined by BCR::ABL1-induced enhancer reprogramming and hypersensitivity to enhancer-targeting drugs

Ng* HL, Glaser* TL, Robinson ME, Cosgun KN, Malysheva V, Zhu J, Deniz O, Crump NT, Helian K, Innes AJ, Sun L, John G, Zhou H, Kaneshige A, Bai L, Wang S, Spivakov M, Müschen M, Feldhahn N.   +18 more
europepmc   +1 more source

Discovery of oligodendrocyte enhancers that regulate Sox10 expression. [PDF]

PLoS Genet
An H, Fan C, Kim D, Bui H, Park Y.
europepmc   +1 more source