Results 101 to 110 of about 436,299 (263)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Euro zone eastern enlargement and ECB’s voting mechanism reform [PDF]

open access: yes
The present paper analyses the issue of the voting mechanism reform within the ECB, as a consequence of the Eastern enlargement of the EU. Now it is known that beginning with the 1st January 2007 the euro zone will “go east” as Slovenia will be the first
Mihai Sebea
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The Post-Enlargement Migration Experience in the Baltic Labor Markets [PDF]

open access: yes
We use Lithuanian, Latvian and Estonian LFS data (2002-2007) complemented with several other surveys to compare the profile of Baltic temporary workers abroad before and after EU accession with that of stayers and return migrants.
Philips, Kaia, Hazans, Mihails
core  

Identities, Not Money: CEE Countries’ Attitudes to the Euro [PDF]

open access: yesCentral European Journal of International & Security Studies, 2011
The research conducted in this research challenges more conventional views that Central and East European (CEE) countries are driven by financial and materialistic concerns in their attitudes towards the adoption of the Euro.
Michal Parizek
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Immigration Following EU Eastern Enlargement [PDF]

open access: yes
Einwanderung, Einwanderungsrecht, Migrationstheorie, EU-Erweiterung, Osteuropa, EU-Staaten, Immigration, Immigration law, Migration theory, EU enlargement, Eastern Europe, EU ...
Hans-Werner Sinn, Martin Werding
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The Deadlock that never Happened: the Impact of Enlargement on the Common Foreign and Security Policy Council Working Groups [PDF]

open access: yes
Contrary to some previous assumptions, the enlargement did not halt the Common Foreign and Security Policy (CFSP) decision-making process in a substantial way.
Karolina Pomorska, Ana E. Juncos
core  

Aetiology and treatment options of gingival enlargement

open access: yes, 2023
This literature review delves into the topic of gingival enlargement, exploring various etiologies that contribute to the development of this condition.
Maktabi, Leila Sadat
core  

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