Results 81 to 90 of about 436,299 (263)

Knocking NATO: Strategic and institutional challenges risk the future of Europe’s seven-decade long cold peace

open access: yesThe School of Public Policy Publications, 2019
Despite providing European stability through collective defence and crisis management in an exclusive club, NATO faces persistent challenges from strategic insecurities complicated by recent institutional uncertainties.
Anessa L. Kimball
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Implications of EMU enlargement for European monetary policy: A political economy view [PDF]

open access: yes
EU Enlargement, Economic Convergence, Political ...
Philipp Maier, Maarten Hendrikx
core  

Labour migration flows: EU8+2 vs EU-15

open access: yesJournal of Business Economics and Management, 2014
The aim of this paper is to determine whether, and to what extent, the migrations from the EU-8+2 to the EU-15 were motivated by differences in earnings and productivity and to what extent by differences in welfare state generosity during the period of ...
Kosta Josifidis   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Enlargement of the European Union: A movement towards the optimal trade bloc size? [PDF]

open access: yes
This paper analyses how the enlargement of a trade bloc will affect national welfare. We establish a partial equilibrium model of a trade bloc either operating as a monopoly with a competitive fringe or facing a duopolistic game in production taxes ...
Glebe, Thilo W.
core  

The European Economic Community's Third Enlargement. Jean Monnet/Robert Schuman Paper Series Vol. 12 No. 6, June 2012 [PDF]

open access: yes, 2012
The European Economic Community's third enlargement round brought up a series of tensions between member states, which would require a great amount of time and effort to be solved. Bigger issues, such as the British contribution, the community budget
Cunha, Alice
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

EU ENLARGEMENT - A NEW DIMENSION [PDF]

open access: yes
Enlarging the EU presents a tremendous effort with obstacles for old and new member states especially in the agricultural sector. In this paper, impacts of a new accession round were analyzed with the help of the comparative-static general equilibrium ...
Herok, Claudia Anna   +3 more
core  

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