Results 131 to 140 of about 436,299 (263)

Poles Apart? EU Enlargement and the Labour Market Outcomes of immigrants in the UK [PDF]

open access: yes
The UK was one of only three countries to allow migrants from accession countries to enter their labour markets more or less without restriction following EU enlargement in May 2004.
Stephen Drinkwater   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Labor market and eu enlargement: is there a real threat for EU – 15? [PDF]

open access: yes
The general implications of globalization as well as those resulting from 2004 and 2007 enlargements have forced EU to think seriously about approaching issues related to rigidity and stagnation in the major EU economies.
Florin Bonciu
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

CIS-7 Perspective on Trade with EU in the Context of EU Enlargement [PDF]

open access: yes
The paper analyses possible consequences of the EU enlargement on the EU – CIS-7 trade. It considers current situation in trade between two country groups, describes the factors limiting this trade, and discusses the opportunities for the trade ...
Roman Mogilevsky
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The monetary policy consequences of enlargement [PDF]

open access: yes
Europäische Wirtschafts- und Währungsunion, EU-Erweiterung, Geldpolitik, European Economic and Monetary Union, EU enlargement, Monetary ...
Carsten Hefeker
core  

"The Geography of the Eastern Enlargement: Present and Future Limits" [PDF]

open access: yes, 2007
[From the introduction]. On January 1st, 2007 the accession of Bulgaria and Romania completed the enlargement of the European Union (EU) to ten Central and Eastern European (CEE) states. The same countries have also become NATO members.
Tudoroiu, Theodor.
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Enlargement: The Challenge of Migration from the New Member States [PDF]

open access: yes
Wirtschaftsintegration, EU-Erweiterung, Wirtschaftspolitik, Mobilität, Europäische Wirtschafts- und Währungsunion, Economic integration, EU enlargement, Economic policy, Mobility, European Economic and Monetary ...
Georges de Menil
core  

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