Results 51 to 60 of about 487,006 (336)

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

The Thoracic Inlet Length as a Reference Point to Radiographically Assess Cardiac Enlargement in Dogs with Myxomatous Mitral Valve Disease [PDF]

, 2023
David Marbella Fernández, Verónica García, Alexis José Santana, José Alberto Montoya-Alonso   +3 more
openalex   +1 more source

What do citizens want? And why does it matter? Discourses among citizens as opportunities and constraints for EU enlargement

, 2017
This article examines the role of citizens’ discourses as constraints and opportunities for future enlargements. Public opinion is an increasingly important factor influencing EU’s integration capacity.
A. Dimitrova, E. Kortenska
semanticscholar   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

The Ventricular System Enlarges Abnormally in the Seventies, Earlier in Men, and First in the Frontal Horn: A Study Based on More Than 3,000 Scans

Frontiers in Aging Neuroscience, 2019
Objectives: To detect on computed tomography (CT) brain scans the trajectories of normal and abnormal ventricular enlargement during aging.Methods: For each 1-year age cohort, we assessed in 3,193 axial CT scans the Evans’ index (EI) in the anterior ...
Antonio Currà, Francesco Pierelli, Riccardo Gasbarrone, Daniela Mannarelli, Italo Nofroni, Vittoria Matone, Lucio Marinelli, Lucio Marinelli, Carlo Trompetto, Carlo Trompetto, Francesco Fattapposta, Paolo Missori   +11 more
doaj   +1 more source

Enlarging Instruction Streams [PDF]

IEEE Transactions on Computers, 2007
The stream fetch engine is a high-performance fetch architecture based on the concept of an instruction stream. We call a sequence of instructions from the target of a taken branch to the next taken branch, potentially containing multiple basic blocks, a stream.
Santana Jaria, Oliverio J., Ramírez Bellido, Alejandro, Valero Cortés, Mateo   +2 more
openaire   +4 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement

Nature Communications, 2015
Long-term potentiation (LTP) is a form of synaptic plasticity that results in enhanced synaptic strength. It is associated with the formation and enlargement of dendritic spines—tiny protrusions accommodating excitatory synapses.
Qinhua Gu, Danni Yu, Zhonghua Hu, Xing Liu, Yanqin Yang, Yan Luo, Jun Zhu, Zheng Li   +7 more
semanticscholar   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Relevance of Copenhagen Criteria in Actual Accession: Principles, Methods and Shortcomings of EU Pre-accession Evaluation [PDF]

Studies of Transition States and Societies, 2011
This paper will analyse the transparency, impartiality and objectiveness of the European Union’s (EU) pre-accession assessment procedure. The principal aim is to test and analyse whether the EU follows official and objective criteria in its progress ...
Viljar Veebel
doaj