EU Enlargement, Identity and the Analysis of European Foreign Policy: Identity Formation through Policy Practice [PDF]
The eastern enlargement of the EU provides an excellent vantage point to examine the interplay of EU identity and European foreign policy. Yet most analysis of eastern enlargement either focus on enlargement as a case of EU foreign policy or on ...
Ulrich Sedelmeier
core
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Regional Input on the Social Dimension of Ezoneplus: Belgium, The Netherlands, France, Austria, and Germany [PDF]
This Regional Input is a supplement to Ezoneplus Working Paper No. 13 on the Social Dimension of the Eastward Enlargement of the Eurozone. Within Ezoneplus the Social Dimension is a hybrid in the sense that it addresses both the reshaping of certain ...
Achim Kemmerling
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Relationship with the European Union: Slovenia and Montenegro Compared
Politics in Central Europe, 2020 As part of former Yugoslavia and non -members of the Eastern Bloc, Slovenia and Montenegro enjoyed a special status and relationships with the European Communities (EC) before most other socialist countries.
Djurovic Gordana, Lajh Damjan
doaj +1 more source
ÒCoreper EnlargedÓ: how Enlargement Affected the Functioning of the Committee of Permanent Representatives [PDF]
Before enlargement, many experts expected that the functioning of most EU institutions would be severely affected by the accession of the ten new member states in 2004.
Jakob Lempp
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source