Results 91 to 100 of about 177,036 (313)

Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-akt pathway [PDF]

open access: yes, 2004
Brief intermittent episodes of ischemia and reperfusion, at the onset of reperfusion after a prolonged period of ischemia, confer cardioprotection, a phenomenon termed "ischemic postconditioning" (Postcond).
Hausenloy, D.J.   +3 more
core  

Disruption of COX-2 and eNOS does not confer protection from cardiovascular failure in lipopolysaccharide-treated conscious mice and isolated vascular rings [PDF]

open access: yes, 2011
It was hypothesized that a serial stimulation of vascular cyclooxygenase-2 (COX-2) with subsequent activation of endothelial nitric oxide synthase (eNOS) is responsible for decrease in blood pressure, cardiac performance, and vascular reactivity in ...
Hansen, Pernille B   +4 more
core   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang   +6 more
wiley   +1 more source

A computational model for analysis of uncoupled NO synthase on nitric oxide and superoxide interaction in microcirculation [PDF]

open access: yes, 2007
Nitric oxide (NO) produced by endothelial cells is a key component for blood-vessel dilation. Dilation is achieved through smooth muscle relaxation as a response to NO transport.
Kavdia, Mahendra, Richardson, William
core   +2 more sources

Effects of acute consumption of fruit and vegetable puree-based drinks on vasodilation and oxidative status [PDF]

open access: yes, 2012
Epidemiological studies indicate that diets rich in fruits and vegetables (F&V) are protective against cardiovascular diseases (CVD). Pureed \&V products retain many beneficial components, including flavonoids, carotenoids, vitamin C and dietary fibres ...
George, Trevor   +4 more
core   +1 more source

Fabrication and Characterisation of Ni/Ti/Ni/Ti Multilayer Thin Film Systems for Hydrogen Storage Applications

open access: yesphysica status solidi (a), EarlyView.
Ni/Ti/Ni/Ti multilayer thin films were fabricated via electron‐beam evaporation and analysed using rutherford backscattering spectrometry and elasticrecoil detection analysis (ERDA). RBS confirmed Ni purity and oxygen in Ti, while ERDA revealed temperature‐dependent hydrogen uptake, peaking at 46.42 at.% at 200 °C. Nickel‐enhanced hydrogen dissociation
Enos Nemukula   +5 more
wiley   +1 more source

Climate warming, euxinia and carbon isotope perturbations during the Carnian (Triassic) Crisis in South China [PDF]

open access: yes, 2016
The Carnian Humid Episode (CHE), also known as the Carnian Pluvial Event, and associated biotic changes are major enigmas of the Mesozoic record in western Tethys.
Bond, D.P.G.   +8 more
core   +2 more sources

Hepatocyte‐specific eNOS deletion impairs exercise‐induced adaptations in hepatic mitochondrial function and autophagy

open access: green, 2022
Rory P. Cunningham   +9 more
openalex   +2 more sources

Emerging Biomedical Engineering Therapies for Infected Diabetic Foot Ulcers: Toward Antibacterial Functionalization and Pathology‐Responsive Regulation

open access: yesSmall Science, EarlyView.
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao   +8 more
wiley   +1 more source

Prognostic significance of three endothelial nitric oxide synthase (eNOS) polymorphisms and metabolic syndrome (MetS) in patients with colorectal cancer

open access: green, 2022
Eun Ju Ko   +10 more
openalex   +2 more sources

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