Results 241 to 250 of about 177,036 (313)

Anti‐Inflammatory Effect of 21α‐Methylmelianol In Vitro and In Vivo via NF‐κB/STAT Signaling Pathway Modulation

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
This study investigated the anti‐inflammatory effects of 21α‐methylmelianol (MMN), a tirucallane triterpenoid isolated from Melia azedarach, in lipopolysaccharide‐ stimulated RAW264.7 macrophages in vitro, and in a dextran sodium sulfate‐induced ulcerative murine colitis model in vivo. ABSTRACT Melia azedarach L., also known as the chinaberry tree, has
Fan Cao, Hua Wu, Zhen He, Mengxin Di, Bin Liu, Zhenwei Chen, Jieming Xie, Yonghong Zhang, Xinhua Ma   +8 more
wiley   +1 more source

Comparative Genomics of Lactococcus spp. From Global Aquaculture Outbreaks Reveals Virulence Determinants, Antibiotic Resistance, and Phage Defence Mechanisms

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Lactococcus petauri predominated in isolates from outbreaks of lactococcosis, suggesting a shift in disease aetiology. Genomic analysis revealed diverse virulence factors, prophage and resistance genes, while antimicrobial susceptibility testing showed uniform resistance to common antibiotics found in farming systems, emphasising the need for ...
Adam M. Blanchard, Bailey Secker, Robert J. Atterbury, Samantha J. Windle, Ha Thanh Dong, Janchai Wongkaew, Le Thanh Dien, David Huchzermeyer, Bernard Mudenda Hang'ombe, Saengchan Senapin   +9 more
wiley   +1 more source

Elastin Regulation of Vasoreactivity in Resistance Arteries. [PDF]

Hypertension
Ruddiman CA, O'Donnell BL, Wolpe A, Blagrove N, Dunaway LS, Lin CJ, Best AK, Cortese-Krott MM, Mecham RP, Wagenseil JE, Isakson BE.   +10 more
europepmc   +1 more source

Hydrogen Sulfide and Nitric Oxide Improve Renal Function and α-Adrenergic Responsiveness in Rats with Left Ventricular Hypertrophy. [PDF]

Curr Issues Mol Biol
Fatima T, Shammari LA, Lazhari MI, Alrohily W, Yong Chia T, Alsabeelah N, Alanazi EF, Almutairi KA, Alhabradi SM, Alharbi NS, Ahmad A.   +10 more
europepmc   +1 more source

Caveolin-1 regulates lipid droplet metabolism in endothelial cells via autocrine prostacyclin–stimulated, cAMP-mediated lipolysis [PDF]

, 2018
Gross, Richard W., Kuo, Andrew, Lee, Monica Y., Sessa, William C., Yang, Kui   +4 more
core   +2 more sources

'Eno-Humanas' - Climate and Environment Models for the Grape Growing and Wine Production Industry

, 2008
Philip Sallis
openalex   +1 more source

Glucagon-like peptide-1 affects human umbilical vein endothelial cells in high glucose by the PI3K/Akt/eNOS signaling pathway

, 2017
Jie Wu, Pingfan Guo, Tianmin He, Fanggang Cai   +3 more
openalex   +1 more source

PRMT1 in Health and Disease: Emerging Perspectives From Molecular Mechanisms to Therapeutic Strategies

MedComm, Volume 6, Issue 12, December 2025.
Protein arginine methyltransferase 1 (PRMT1) is a pivotal enzyme that catalyzes the asymmetric dimethylation of arginine residues, thereby functioning as a critical epigenetic regulator of diverse biological processes such as gene expression, RNA splicing, and DNA repair.
Yanqun Luo, Ying Gao, Xiaoliang Deng, Lei Wang, Tao Wu   +4 more
wiley   +1 more source

Interleukin 10 enhances endothelial progenitor cell-mediated angiogenesis in extrahepatic portal venous obstruction. [PDF]

Stem Cell Res Ther
Zhang JS.
europepmc   +1 more source

Inflammasome Activation Differences Underpin Different Mycobacterium tuberculosis Infection Outcomes

MedComm, Volume 6, Issue 12, December 2025.
Summary: PAMPS of Mtb interacts with PRRs of host cells and activates intracellular signaling, leading to activation of the inflammasome complex, which differentially contributes to the progressive or nonprogressive Mtb infection. We report a novel mechanism of inflammasome activation mediated by GBP1 and HIF‐1α, which orchestrates differential ...
Ranjeet Kumar, Afsal Kolloli, Gunapati Bhargavi, Seema Husain, Theresa L. Chang, Saleena Ghanny, Patricia Soteropoulos, Selvakumar Subbian   +7 more
wiley   +1 more source