Results 241 to 250 of about 100,569 (330)

Molecular and Biochemical Mechanisms of Cardiomyopathy Development Following Prenatal Hypoxia-Focus on the NO System. [PDF]

Antioxidants (Basel)
Popazova O, Belenichev I, Bukhtiyarova N, Ryzhenko V, Gorchakova N, Oksenych V, Kamyshnyi O.   +6 more
europepmc   +1 more source

Celiprolol Activates eNOS Through the PI3K-Akt Pathway and Inhibits VCAM-1 Via NF-κB Induced by Oxidative Stress [PDF]

, 2003
Naohiko Kobayashi, Shin-ichiro Mita, Kohtaro Yoshida, Takeaki Honda, Tsutomu Kobayashi, Kazuyoshi Hara, Shigefumi Nakano, Yusuke Tsubokou, Hiroaki Matsuoka   +8 more
openalex   +1 more source

Lipocalin‐2 Restores Soluble Guanylyl Cyclase‐Dependent Dilation of the Afferent Arteriole After Renal Transplantation or Ex Vivo Hypoxia/Reoxygenation in Mice

Acta Physiologica, Volume 241, Issue 8, August 2025.
ABSTRACT Aim Dilatory microvascular function is impaired in ischemia/reperfusion injury in the kidney. Nitric oxide independent activators of soluble guanylyl cyclase (sGC) provide renal protection by dilating microvessels and preserving perfusion, but their efficacy declines after severe hypoxia.
Liang Zhao, Minze Xu, Anna Maria Pfefferkorn, Cem Erdogan, Hubert Schwelberger, Pinchao Wang, Pratik Hemant Khedkar, Marc Eigen, Falk‐Bach Lichtenberger, Rusan Catar, En Yin Lai, Felix Aigner, Pontus B. Persson, Igor Maximilian Sauer, Andreas Patzak, Muhammad Imtiaz Ashraf   +15 more
wiley   +1 more source

Sinusoidal Extremely Low-Frequency Electromagnetic Stimulation (ELF-EMS) Promotes Angiogenesis In Vitro. [PDF]

Biomedicines
Font LP, Moya-Gomez A, Kemps H, Lambrichts I, Rigo JM, Brône B, Bronckaers A.   +6 more
europepmc   +1 more source

Synergistic Activation of Endothelial Nitric-oxide Synthase (eNOS) by HSP90 and Akt [PDF]

, 2003
Satoru Takahashi, Michael E. Mendelsohn
openalex   +1 more source

Effects of gestational intermittent hypoxia on the respiratory system: A tale of the placenta, fetus, and developing offspring

Journal of Sleep Research, Volume 34, Issue 4, August 2025.
Effects of gestational intermittent hypoxia on maternal, fetal and offspring respiratory system. In black, effects in humans; in red, in vitro effects; in blue, effects in animal models. Summary Obstructive sleep apnea (OSA) is a common sleep disorder that is associated with a wide variety of health conditions, including cardiovascular, cerebrovascular,
Esther Valverde‐Pérez, Elena Olea, Asunción Rocher, Philip I. Aaronson, Jesús Prieto‐Lloret   +4 more
wiley   +1 more source

The Regulatory Mechanisms of Treponema pallidum Enolase on Macrophages: From Enzymatic Activity to Signal Transduction

The FASEB Journal, Volume 39, Issue 13, 15 July 2025.
ABSTRACT Syphilis, caused by the gram‐negative bacterium Treponema pallidum, remains a significant global public health threat. Despite the efficacy of antibiotic treatment in controlling syphilis, the pathogenic mechanisms of T. pallidum, particularly its interactions with the host immune system, are not well understood.
Peiyuan Sun, Suo Liu, Qilin Zeng, Weiwei Li, Sijia Li, Zhanpeng Wang, Yuanyuan Tang, Hongyu Yang, Dongde Xie, Jun Zhou, Yanxia Zhou, Kang Zheng, Yimou Wu   +12 more
wiley   +1 more source

Inducible nitric oxide synthase (iNOS): More than an inducible enzyme? Rethinking the classification of NOS isoforms. [PDF]

Pharmacol Res
Farahani A, Farahani A, Kashfi K, Ghasemi A.   +3 more
europepmc   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, Volume 12, Issue 25, July 3, 2025.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

Intermedin_1-53 Improves Atherosclerosis by Reducing Local Endothelial Damage via AMPK Signaling Pathway in Obese apoE-Deficient Mice. [PDF]

J Inflamm Res
Zhu HX, Ren JL, Cao WJ, Wang R, Chen LL, Gao Q, Zhou YB.   +6 more
europepmc   +1 more source