Results 251 to 260 of about 100,569 (330)
Safflower injection against obesity-induced mice podocyte injury by improving insulin resistance through increasing renal INSR and eNOS expression. [PDF]
Han Z+5 more
europepmc +1 more source
Neurotoxicity of Hcy. (A figure that best represents the scope of the paper.) Homocysteine can reduce the tightness of endothelial cell connections, increase vascular permeability, and damage the blood–brain barrier. Homocysteine activates various glutamate receptors on the surfaces of neurons and glial cells, triggering excitotoxicity, promoting the ...
Bin Li, Yushun Kou, Lingna Zhang, Lin Yi
wiley +1 more source
The potential role of nitrate, a nitric oxide donor, in the prevention and treatment of diabetic osteoporosis. [PDF]
Jeddi S, Kashfi K, Ghasemi A.
europepmc +1 more source
This systematic review and meta‐analysis evaluated the therapeutic efficacy of Astragaloside IV in ischemic heart disease, encompassing 18 preclinical studies. The findings demonstrated that As‐IV significantly reduced myocardial infarction size and apoptosis while improving cardiac function and angiogenesis through various mechanisms, along with ...
Alosh Greeny+7 more
wiley +1 more source
The renoprotective effects of tadalafil on ischemia-reperfusion injury during partial nephrectomy in an animal model. [PDF]
Lee EH+9 more
europepmc +1 more source
Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar+10 more
wiley +1 more source
Aortic Valve Defect as an Independent Risk Factor for Endothelial Dysfunction. [PDF]
Malina M, Banasiak W, Doroszko A.
europepmc +1 more source