Results 41 to 50 of about 608,686 (265)

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Factorization homology of enriched $\infty$-categories

, 2017
For an arbitrary symmetric monoidal $\infty$-category $\mathcal{V}$, we define the factorization homology of $\mathcal{V}$-enriched $(\infty,1)$-categories over (possibly stratified) 1-manifolds and study some of its basic properties. In the case of spectral enrichment, we show that the value of factorization homology on a circle is topological ...
Ayala, David, Francis, John, Mazel-Gee, Aaron, Rozenblyum, Nick   +3 more
openaire   +2 more sources

Seed genome hypomethylated regions are enriched in transcription factor genes [PDF]

Proceedings of the National Academy of Sciences, 2018
Significance We scanned soybean and Arabidopsis seed genomes for hypomethylated regions, or DNA methylation valleys (DMVs), present in mammalian cells. Seeds contain DMV regions that have <5% bulk DNA methylation or, in many cases, no detectable DNA methylation ...
Chen, Min, Lin, Jer-Young, Hur, Jungim, Pelletier, Julie M, Baden, Russell, Pellegrini, Matteo, Harada, John J, Goldberg, Robert B   +7 more
openaire   +4 more sources

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Determination of heavy metal pollutions in the atmospheric falling dust by multivariate analysis [PDF]

Caspian Journal of Environmental Sciences, 2019
The purpose of this study was to assess some heavy metal (HM) concentrations in the soil and atmospheric falling dust along the Yazd highway, Yazd Province, Iran. The total concentrations of cadmium (Cd), cobalt (Co), copper (Cu), nickle (Ni), lead (Pb),
M. Esfandiari, H. Sodaiezadeh, M.A. Hakimzadeh Ardakani, M.H. Mokhtari   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The influence of environmental drivers on the enrichment of organic carbon in the sea surface microlayer and in submicron aerosol particles – measurements from the Atlantic Ocean

Elementa: Science of the Anthropocene, 2017
The export of organic matter from ocean to atmosphere represents a substantial carbon flux in the Earth system, yet the impact of environmental drivers on this transfer is not fully understood. This work presents dissolved and particulate organic carbon (
Manuela van Pinxteren, Stefan Barthel, Khanneh Wadinga Fomba, Konrad Müller, Wolf von Tümpling, Hartmut Herrmann   +5 more
doaj   +1 more source

isotopic enrichment factor

, 2014
Citation: 'isotopic enrichment factor' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.I03342 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Dependence of the amplification factor on the body water deuterium enrichment

Journal of Immunological Methods
Heavy water (D2O) labeling is the state-of-the-art technique to track the dynamics of circulating cells in vivo. D2O labels dividing cells through incorporation of deuterium into newly synthesized DNA, which is measured using GC/MS. The labeling rate depends on (1) the level of body water enrichment, (2) cell kinetics, and (3) an amplification factor ...
Erdem Şanal, Julia Drylewicz, Kiki Tesselaar, Becca Asquith, José A.M. Borghans, Rob J. de Boer   +5 more
openaire   +3 more sources