Results 81 to 90 of about 608,686 (265)

On the enrichment of random factors models

open access: yes, 2017
To test the main e ects and interactions in random e ects models we consider an orthogonal partition in subspaces associated to the subset of factors. Availing ourselves of the much larger dimension of one of the subspaces in the orthogonal partition, we enrich the model by imbedding linear regressions.
Nunes, Célia   +4 more
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Potentially Toxic Elements in Terrestrial Mosses in the Vicinity of a Stibnite Mine in Pinal de Amoles, Mexico

open access: yesPlants
Mining waste often contains elevated concentrations of V, Cr, As, Sb, and Pb. Stibnite mining, during extraction and processing, generates waste that is deposited directly onto soil without vegetation cover, potentially leading to environmental pollution.
Samuel Tejeda   +6 more
doaj   +1 more source

Heavy metal levels in surface waters from a tropical river basin, Pernambuco State, northeastern Brazil - doi: 10.4025/actascibiolsci.v32i4.5231

open access: yesActa Scientiarum: Biological Sciences, 2010
Monthly, the distribution and enrichment of heavy metals (Fe, Mn, Cu, Pb and Zn) in surface waters were examined at eight sampling sites, in Tapacurá river (Pernambuco State, Brazil), from March 1997 to December 1998 and from June 2005 to March 2006.
Fábio Marques Aprile, Marc Bouvy
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Mineralogical and elemental analysis of Kazakh coals from three mines: Preliminary insights from mode of occurrence to environmental impacts

open access: yesOpen Geosciences
This study aims to comprehensively characterize coal extracted from three active mines in northeastern Kazakhstan: Lenin, Saradyr, and Bogatyr. These mines exploit two Carboniferous coal-bearing formations, Dolyn and Karagandy.
Junussov Medet   +5 more
doaj   +1 more source

Polyglutamine and Polyalanine Tracts Are Enriched in Transcription Factors of Plants.

open access: yes, 2012
Polyglutamine (polyQ) tracts have been studied extensively for their roles in a number of human diseases such as Huntington's or different Ataxias. However, it has also been recognized that polyQ tracts are abundant and may have important functional and evolutionary roles.
Kottenhagen, Nina   +4 more
openaire   +3 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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