Results 131 to 140 of about 508,769 (269)

Potassium enrichment mechanism and controlling factors in Cambrian black shale from eastern Guizhou, China. [PDF]

Sci Rep
Fu J, Tu L, Zhao S, Jiang T, Pan W, Cheng W, Shi C, Yang R, Li Y, Gao J.   +9 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Preparation of Amphiphilic Janus-SiO2 Nanoparticles and Evaluation of the Oil Displacement Effect

ACS Omega
Shanfa Tang, Zhiguo Sun, Yuanwu Dong, Yangwen Zhu, Hao Hu, Rui Wang, Haiying Liao, Quanqi Dai   +7 more
doaj   +1 more source

Study on the Weathering Process and Re-enrichment Mechanism of the Ediacaran Phosphorus Deposits in Central Guizhou, China. [PDF]

ACS Omega
Yang C, Xie H, Li Z, Wang M, Wang Y.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Enrichment Mechanism of Organic Matter in the Marine-Continental Transitional Shale of the Taiyuan Formation in Ordos Basin, China: Control of the Paleoenvironment. [PDF]

ACS Omega
He Z, Yang M, Wang L, Lu J, Wang Y, Peng X, Shao L.   +6 more
europepmc   +1 more source

Mechanical characterization of bone allografts, enriched with mesenchymal cells

International Journal of Design & Nature and Ecodynamics, 2016
JOSÉ LUIS DÍAZ LEÓN, RAÚL LESSO ARROYO, RAMÓN RODRÍGUEZ CASTRO, ALFONSO LÓPEZ VÁZQUEZ   +3 more
openaire   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Paleoenvironment reconstruction and differential OM enrichment mechanism of the Upper Triassic Chang 7 member source rocks in the Ordos Basin. [PDF]

Sci Rep
Sun K, Chen G, Zhou X, Yong J, Xu Y, Wang N, Dong J.   +6 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source