Results 1 to 10 of about 306,517 (268)

A silylene-stabilized ditin(0) complex and its conversion to methylditin cation and distannavinylidene

Nature Communications, 2023
Due to their intrinsic high reactivity, isolation of tin(0) complexes remains challenging. Herein, we report the synthesis of a silylene-stabilized ditin(0) complex (2) by reduction of a silylene-supported dibromostannylene (1) with 1 equivalent of ...
Shaozhi Du, Fanshu Cao, Xi Chen, Hua Rong, Haibin Song, Zhenbo Mo   +5 more
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Direct allylic acylation via cross-coupling involving cooperative N‑heterocyclic carbene, hydrogen atom transfer, and photoredox catalysis

Nature Communications, 2023
Herein, we report a mild, operationally simple, multicatalytic method for the synthesis of β,γ-unsaturated ketones via allylic acylation of alkenes. Specifically, the method combines N‑heterocyclic carbene catalysis, hydrogen atom transfer catalysis, and
Xiaochen Wang, Rongxin Yang, Binbing Zhu, Yuxiu Liu, Hongjian Song, Jianyang Dong, Qingmin Wang   +6 more
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Design, Synthesis, and Bioactivities of Novel Tryptophan Derivatives Containing 2,5-Diketopiperazine and Acyl Hydrazine Moieties

Molecules, 2022
Based on the scaffolds widely used in drug design, a series of novel tryptophan derivatives containing 2,5-diketopiperazine and acyl hydrazine moieties have been designed, synthesized, characterized, and evaluated for their biological activities.
Lili Li, Rongxin Yang, Jianhua Liu, Jingjing Zhang, Hongjian Song, Yuxiu Liu, Qingmin Wang   +6 more
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Ketone α-alkylation at the more-hindered site

Nature Communications, 2023
Control of the regioselectivity of α-alkylation of carbonyl compounds is a longstanding topic of research in organic chemistry. By using stoichiometric bulky strong bases and carefully adjusting the reaction conditions, selective alkylation of ...
Ming-Ming Li, Tianze Zhang, Lei Cheng, Wei-Guo Xiao, Jin-Tao Ma, Li-Jun Xiao, Qi-Lin Zhou   +6 more
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Promoting Efficacy and Environmental Safety of Pesticide Synergists via Non-Ionic Gemini Surfactants with Short Fluorocarbon Chains

Molecules, 2022
Improving the utilization rate of pesticides is key to achieve a reduction and synergism, and adding appropriate surfactant to pesticide preparation is an effective way to improve pesticide utilization.
Ruiguo Wang, Xinxin Xu, Xiaodi Shi, Junjie Kou, Hongjian Song, Yuxiu Liu, Jingjing Zhang, Qingmin Wang   +7 more
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Facile and general electrochemical deuteration of unactivated alkyl halides

Nature Communications, 2022
Deuterium-labelled compounds are useful for mechanistic studies and pharmaceutical science, but syntheses are not trivial. Here, the authors report deuteration of unactivated alkyl (pseudo)halides driven by electrochemical force, using deuterium oxide as
Pengfei Li, Chengcheng Guo, Siyi Wang, Dengke Ma, Tian Feng, Yanwei Wang, Youai Qiu   +6 more
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Metal-free electrochemical dihydroxylation of unactivated alkenes

Nature Communications, 2023
Herein, a metal-free electrochemical dihydroxylation of unactivated alkenes is described. The transformation proceeds smoothly under mild conditions with a broad range of unactivated alkenes, providing valuable and versatile dihydroxylated products in ...
Min Liu, Tian Feng, Yanwei Wang, Guangsheng Kou, Qiuyan Wang, Qian Wang, Youai Qiu   +6 more
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Design, Synthesis, and Bioactivity Study of Novel Tryptophan Derivatives Containing Azepine and Acylhydrazone Moieties

Molecules, 2022
Based on the scaffolds widely used in drug design, a series of novel tryptophan derivatives containing azepine and acylhydrazone moieties have been designed, synthesized, characterized, and evaluated for their biological activities.
Jingjing Zhang, Rongxin Yang, Lili Li, Jianhua Liu, Yuxiu Liu, Hongjian Song, Qingmin Wang   +6 more
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Suppression of alpha-carbon racemization in peptide synthesis based on a thiol-labile amino protecting group

Nature Communications, 2023
In conventional solid-phase peptide synthesis (SPPS), α-amino groups are protected with alkoxycarbonyl groups (e.g., 9-fluorenylmethoxycarbonyl [Fmoc]).
Yifei Zhou, Hongjun Li, Yi Huang, Jiahui Li, Guiyu Deng, Gong Chen, Zhen Xi, Chuanzheng Zhou   +7 more
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Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues

Molecules, 2023
Compounds with acylhydrazone fragments contain amide and imine groups that can act as electron donors and acceptors, so they are easier to bind to biological targets and thus generally exhibit significant biological activity.
Wanjun Ni, Hongjian Song, Lizhong Wang, Yuxiu Liu, Qingmin Wang   +4 more
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