Synthesis and Anti-TMV Activity of Dialkyl/dibenzyl 2-((6-Substituted-benzo[d]thiazol-2-ylamino)(benzofuran-2-yl)methyl) Malonates [PDF]
Molecules, 2013 Starting from benzofuran-2-methanal, 6-substituted benzothiazole-2-amines and malonic esters, sixteen title compounds were designed and synthesized seeking to introduce anti-TMV activity.
Meichuan Li +8 more
doaj +5 more sources
Gene editing, metabolomics, network pharmacology strategies to explore terpenoid content and anti-TMV activity in NtSPS1 knockout Nicotiana tabacum [PDF]
Scientific ReportsThe content of terpenoids in tobacco can alter its resistance to TMV. NtSPS1, a pivotal structural gene in tobacco, is capable to regulate the terpenoid content.
Jia-Meng Dai +9 more
doaj +3 more sources
Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity [PDF]
Molecules, 2013 Phytochemical investigations of the leaves of Garcinia paucinervis resulted in the isolation of three new xanthones 1–3 and five known analogues 4–8. Structural elucidations of 1–3 were performed by spectral methods such as 1D and 2D (HMQC, HMBC, and ...
Qiu-Fen Hu +6 more
doaj +3 more sources
Metabolites Produced by an Endophytic Phomopsis sp. and Their Anti-TMV Activity [PDF]
Molecules, 2017 The fermentation and isolation of metabolites produced by an endophytic fungus, which was identified as Phomopsis sp. FJBR-11, based on phylogenetic analysis, led to the identification of six compounds, including dothiorelones A–C, and H, and ...
Qing-Wei Tan +4 more
doaj +3 more sources
Plant-Derived Anti-TMV Metabolites: Mechanisms, Limitations and Future Perspectives [PDF]
VirusesTobacco mosaic virus (TMV) poses a serious threat to global agricultural production. It is an exceptionally stable virus with a broad host range and is widespread across diverse agroecosystems.
Muhammad Qasim Aslam +8 more
doaj +2 more sources
Systemic infection of tobacco mosaic virus is limited by upward transport and phloem unloading without coat protein. [PDF]
Plant JSUMMARY Coat protein (CP) is widely viewed as essential for systemic infection of tobacco mosaic virus (TMV), yet the mechanistic basis of this requirement remains incompletely resolved. In this study, we show that TMV can still achieve long‐distance vascular transport in the absence of CP, but systemic infection becomes intermittent because the ...
Jung M, Kim KH.
europepmc +2 more sources
Signaling Pathway Analysis and Downstream Genes Associated with Disease Resistance Mediated by GmSRC7 [PDF]
PlantsGmSRC7 is a broad-spectrum antiviral R gene from soybean, but its downstream and functionally related genes remain unclear. Virus-induced gene silencing (VIGS) assays in Nicotiana benthamiana (Nb) showed that suppression of several gene families—WRKY ...
Aoga Li +8 more
doaj +2 more sources
Role of a Synonymous Mutation at Codon 178 in P1 That Attenuates Potato Virus Y-Induced Tobacco Vein Necrosis and Its Application for Expressing Human Interferon. [PDF]
Mol Plant PatholA synonymous mutation at P1 K178 attenuates PVY virulence and abolishes tobacco vein necrosis. This attenuated vector serves as a high‐efficiency plant bioreactor for the production and purification of recombinant human interferons. ABSTRACT Plant virus‐based vectors are gaining significant attention as bioreactors for recombinant protein production ...
Liu DG +11 more
europepmc +2 more sources
Molecules, 2015 A series of novel pyrazole amide derivatives 3a–3p which take TMV PC protein as the target has been designed and synthesized by the reactions of 5-chloro-1-aryl-3-methyl-1H-pyrazole-4-carboxylic acids with 5-amino-1-aryl-1H-pyrazole-4-carbonitriles.
Jin-Jing Xiao +6 more
doaj +3 more sources
Synthesis and Evaluation of 11-Butyl Matrine Derivatives as Potential Anti-Virus Agents
Molecules, 2022 Matrine derivatives were reported to have various biological activities, especially the ester, amide or sulfonamide derivatives of matrine deriving from the hydroxyl or carboxyl group at the end of the branch chain after the D ring of matrine is opened ...
Wanjun Ni +4 more
doaj +1 more source