Results 21 to 30 of about 13,208 (153)

Engineering the 3'-UTR of Tobacco Vein Mottling Virus to Confer Cross-Protection Against Potyviruses. [PDF]

Mol Plant Pathol
The 3′‐untranslated region (3′‐UTR) and its secondary structure of virus genomic RNA of tobacco vein mottling virus (TVMV) are important in symptoms attenuation, which can be engineered for cross‐protection against further viral infection. We provide experimental evidence that supports the roles of 3′‐UTR in potyvirus infection.
Wang H, Sun Z, Zhang B, Wu Z, Xu J, Zhao M.   +5 more
europepmc   +2 more sources

Anti-TMV Activities of Pantoea agglomerans Lipopolysaccharides in vitro [PDF]

Mikrobiolohichnyi Zhurnal, 2021
Today there are no antiviral drugs of chemical nature that can completely cure virus-infected plants. The fact that their effect is limited to minimizing the pathogenic effect of viruses motivates many researchers to look for alternatives. In recent years it has been shown that lipopolysaccharides (LPS) of some bacteria, in particular representatives ...
T.V. Bulyhina, A.M. Kyrychenko, M.S. Kharchuk, L.D. Varbanets   +3 more
openaire   +1 more source

Role of a Synonymous Mutation at Codon 178 in P1 That Attenuates Potato Virus Y-Induced Tobacco Vein Necrosis and Its Application for Expressing Human Interferon. [PDF]

Mol Plant Pathol
A synonymous mutation at P1 K178 attenuates PVY virulence and abolishes tobacco vein necrosis. This attenuated vector serves as a high‐efficiency plant bioreactor for the production and purification of recombinant human interferons. ABSTRACT Plant virus‐based vectors are gaining significant attention as bioreactors for recombinant protein production ...
Liu DG, Wang YY, Zhu Q, Huang XW, Yan XY, Jia MA, Guo YS, Cao LG, Jiang J, Li XD, Zhang XL, Tian YP.   +11 more
europepmc   +2 more sources

Synthesis and Evaluation of 11-Butyl Matrine Derivatives as Potential Anti-Virus Agents

Molecules, 2022
Matrine derivatives were reported to have various biological activities, especially the ester, amide or sulfonamide derivatives of matrine deriving from the hydroxyl or carboxyl group at the end of the branch chain after the D ring of matrine is opened ...
Wanjun Ni, Lizhong Wang, Hongjian Song, Yuxiu Liu, Qingmin Wang   +4 more
doaj   +1 more source

1,3,4-Oxadiazole Contained Sesquiterpene Derivatives: Synthesis and Microbiocidal Activity for Plant Disease

Frontiers in Chemistry, 2022
A series of 1,3,4-oxadiazole contained sesquiterpene derivatives were synthesized, and the activity of the target compounds against Xanthomonas oryzae pv. oryzae (Xoo), Xanthomonas axonopodis pv. citri (Xac), and tobacco mosaic virus (TMV) were evaluated.
Ali Dai, Zhiguo Zheng, Lijiao Yu, Yuanqin Huang, Jian Wu   +4 more
doaj   +1 more source

First discovery and stucture-activity relationship study of phenanthroquinolizidines as novel antiviral agents against tobacco mosaic virus (TMV). [PDF]

PLoS ONE, 2012
A series of phenanthroquinolizidine alkaloids 1-24 were prepared and first evaluated for their antiviral activity against tobacco mosaic virus (TMV). The bioassay results showed that most of these compounds exhibited good to excellent in vivo anti-TMV ...
Ziwen Wang, Anzheng Feng, Mingbo Cui, Yuxiu Liu, Lizhong Wang, Qingmin Wang   +5 more
doaj   +1 more source

The curative activity of some arylidene dihydropyrimidine hydrazone against Tobacco mosaic virus infestation

Journal of Saudi Chemical Society, 2022
A series of novel pyrimidine-based derivative compounds were synthesized and evaluated for antiviral activity against Tobacco mosaic virus (TMV).
Alaa Z. Omar, Esraa Hamdy, Ezzat A. Hamed, Elsayed Hafez, Ahmed Abdelkhalek   +4 more
doaj   +1 more source

Tobamoviruses CP Proteins Hijack Light-Induced Protein (NbLIP1) to Promote Viral Replication by Facilitating VRO Formation. [PDF]

Plant Biotechnol J
ABSTRACT Tobamoviruses establish viral replication organelles (VROs) on the host endoplasmic reticulum (ER) for their replication, a process demanding substantial different types of lipids. However, how viruses efficiently transfer these lipids from other compartments like chloroplasts remains incompletely understood.
Chen H, Wu M, Guo X, Xu H, Feng C, Liu D, Hua J, Hua Y, He Z, Moffett P, Zhang K.   +10 more
europepmc   +2 more sources

Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues

Molecules, 2023
Compounds with acylhydrazone fragments contain amide and imine groups that can act as electron donors and acceptors, so they are easier to bind to biological targets and thus generally exhibit significant biological activity.
Wanjun Ni, Hongjian Song, Lizhong Wang, Yuxiu Liu, Qingmin Wang   +4 more
doaj   +1 more source

Discovery of Cysteine and Its Derivatives as Novel Antiviral and Antifungal Agents

Molecules, 2021
Based on the structure of the natural product cysteine, a series of thiazolidine-4-carboxylic acids were designed and synthesized. All target compounds bearing thiazolidine-4-carboxylic acid were characterized by 1H-NMR, 13C-NMR, and HRMS techniques. The
Shan Yang, Tienan Wang, Yanan Zhou, Li Shi, Aidang Lu, Ziwen Wang   +5 more
doaj   +1 more source