Results 1 to 10 of about 233 (133)

Acylhydrazones and Their Biological Activity: A Review

Molecules, 2022
Due to the structure of acylhydrazones both by the pharmacophore –CO–NH–N= group and by the different substituents present in the molecules of compounds of this class, various pharmacological activities were reported, including antitumor, antimicrobial ...
Laura-Ileana Socea, Stefania-Felicia Barbuceanu, Elena Mihaela Pahontu, Alexandru-Claudiu Dumitru, George Mihai Nitulescu, Roxana Corina Sfetea, Theodora-Venera Apostol   +6 more
doaj   +3 more sources

Design, Synthesis and Various Bioactivity of Acylhydrazone-Containing Matrine Analogues

Molecules, 2023
Compounds with acylhydrazone fragments contain amide and imine groups that can act as electron donors and acceptors, so they are easier to bind to biological targets and thus generally exhibit significant biological activity.
Wanjun Ni, Hongjian Song, Lizhong Wang, Yuxiu Liu, Qingmin Wang   +4 more
doaj   +3 more sources

Design, Synthesis, and Insecticidal Activity of Some Novel Diacylhydrazine and Acylhydrazone Derivatives

Molecules, 2015
In this study a series of diacylhydrazine and acylhydrazone derivatives were designed and synthesized according to the method of active group combination and the principles of aromatic group bioisosterism.
Jialong Sun, Yuanming Zhou
doaj   +3 more sources

Antiprotozoal Activity of (E)-Cinnamic N-Acylhydrazone Derivatives [PDF]

Molecules, 2014
A series of 14 (E)-cinnamic N-acylhydrazone derivatives, designed through molecular hybridization between the (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-bromophenyl)prop-2-en-1-one and (E)-3-hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)-7-methoxy-2-naphthohydrazide, were tested for in vitro antiparasitic activity upon axenic amastigote forms of ...
Carvalho, Samir Aquino, Kaiser, Marcel, Brun, Reto, Silva, Edson Ferreira da, Fraga, Carlos Alberto Manssour   +4 more
openaire   +6 more sources

Synthesis and characterization of Molybdenum(VI) complex with 4-methoxy Salicylaldehyde 2-aminobenzoylhydrazon and investigation of their antibacterial activity [PDF]

شیمی کاربردی روز, 2021
In the study, reaction of the 4-methoxy salicylaldehyde 2-aminobenzoylhydrazone(H2L) with MoO2(acac)2 formed a 5-coordinate Molybdenum(VI) complex [MoO2L].
Mahboobeh Moosavi, Niaz Monadi, Mojtaba Mohseni   +2 more
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“In Water” Fabricated and Recycled Covalent Adaptable Acylhydrazone Thermosets

Macromolecular Materials and Engineering, 2023
Thermosetting resins play an increasingly important role in daily life due to their good mechanical properties. However, they can hardly be recycled and reused, leading to severe environmental pollution.
Guanglong Li, Jing Huang, Xuhui Zhang, Yang Wang, Jinliang Qiao, Tianxi Liu, Mingliang Du, Weifu Dong   +7 more
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Design, Synthesis, and Bioactivity Study of Novel Tryptophan Derivatives Containing Azepine and Acylhydrazone Moieties

Molecules, 2022
Based on the scaffolds widely used in drug design, a series of novel tryptophan derivatives containing azepine and acylhydrazone moieties have been designed, synthesized, characterized, and evaluated for their biological activities.
Jingjing Zhang, Rongxin Yang, Lili Li, Jianhua Liu, Yuxiu Liu, Hongjian Song, Qingmin Wang   +6 more
doaj   +1 more source

Synthesis and Biological Evaluation of Benzo[b]thiophene Acylhydrazones as Antimicrobial Agents against Multidrug-Resistant Staphylococcus aureus

Biomolecules, 2022
The benzo[b]thiophene nucleus and the acylhydrazone functional group were combined to prepare three new series of compounds for screening against Staphylococcus aureus.
Thibaut Barbier, Alexia Barbry, Jérémy Magand, Cédric Badiou, Floriane Davy, Anne Baudouin, Yves Queneau, Oana Dumitrescu, Gérard Lina, Laurent Soulère   +9 more
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Assignments of NMR Spectral Data of a Novel Carbazole-Triazinoindole Based N-Acylhydrazone Derivative

Chinese Journal of Magnetic Resonance, 2020
N-acylhydrazone compounds have two isomers, E/cis and E/trans, in polar solvents. In this work, 1H and 13C nuclear magnetic resonance (NMR) signals, coupling constants (J), and the spatial structures of the two isomers (E/cis and E/trans) of a novel ...
LI Ying-jun, YANG Hong-jing, LIU Ji-hong, JIN Kun, LIN Le-di, LIU Xue-jie   +5 more
doaj   +1 more source

Design, Synthesis, and Antifungal Activity of Some Novel Phenylthiazole Derivatives Containing an Acylhydrazone Moiety

Molecules, 2023
Crop fungal diseases pose a serious threat to global crop production and quality. Developing new and efficient fungicides is an important measure to control crop diseases.
Yao Tian, Jinchao Shi, Xiaoqian Deng, Tingyu Yu, Yong Hu, Richa Hu, Yufeng Lei, Linhua Yu, Xiang Zhu, Junkai Li   +9 more
doaj   +1 more source