Results 41 to 50 of about 4,308 (256)

Additional file 4 of Evaluation of antiplasmodial activity in silico and in vitro of N-acylhydrazone derivatives

, 2022
Additional file 4: Figure SAH4.
Fernanda A. Oliveira (13027032), Eder Lorenzato Junior (13027041), Ana Claudia S. Pinto (13027035), Diogo T. Carvalho (4986722), Alex G. Taranto (7396214), Fernando P. Varotti (13027044), Amanda L. Fonseca (13027047), Caique L. Duarte (13027038), Cleydson Finotti Cordeiro (9502386)   +8 more
core   +1 more source

Design, Synthesis, Antinociceptive and Anti-Inflammatory Activities of Novel Piroxicam Analogues

Molecules, 2012
In this paper we report the design, synthesis, antinociceptive and anti-inflammatory activities of a series of benzothiazine N-acylhydrazones 14a–h, planned by structural modification of piroxicam (1), a non steroidal anti-inflammatory drug ...
Eliezer J. Barreiro, Lídia Moreira Lima, Rosane de Paula Castro, José Ricardo Sabino, Luciano Morais Lião, Magna Suzana Alexandre-Moreira, Walfrido Bispo Júnior, Yolanda Karla Cupertino da Silva, Amanda Silva de Miranda   +8 more
doaj   +1 more source

Additional file 7 of Evaluation of antiplasmodial activity in silico and in vitro of N-acylhydrazone derivatives

, 2022
Additional file 7: Figure SAH7.
Fernanda A. Oliveira (13027032), Eder Lorenzato Junior (13027041), Ana Claudia S. Pinto (13027035), Diogo T. Carvalho (4986722), Alex G. Taranto (7396214), Fernando P. Varotti (13027044), Amanda L. Fonseca (13027047), Caique L. Duarte (13027038), Cleydson Finotti Cordeiro (9502386)   +8 more
core   +1 more source

Injectable Acylhydrazone‐Linked RAFT Polymer Hydrogels for Sustained Protein Release and Cell Encapsulation [PDF]

, 2022
A new class of temperature responsive polymer, termed PADO, is synthesized by reversible addition-fragmentation chain-transfer (RAFT) polymerization.
Fang‐Yi Lin, Mariana Moraes de Lima Perini, Jiliang Li, Moraes de Lima Perini, Mariana, Chien‐Chi Lin, Li, Jiliang, Nathan H. Dimmitt, Lin, Chien-Chi, Dimmitt, Nathan H., Lin, Fang-Yi   +9 more
core   +1 more source

Oral Antithrombotic Effects of Acylhydrazone Derivatives

Journal of Atherosclerosis and Thrombosis, 2013
In the search for new antithrombotic drug candidates, the synthesis and anti-platelet activity of a new series of N-acylhydrazones that were designed as thrombin inhibitors has been previously described. The aim of this work was to further characterize the effects of these compounds on thrombin-induced platelet aggregation and induced thrombosis in ...
Frattani, Flávia Serra, Coriolano, Eduardo Oliveira, Lima, Lidia Moreira, Barreiro, Eliezer Jesus, Zingali, Russolina Benedeta   +4 more
openaire   +3 more sources

Discovery of Novel RNA Demethylase FTO Inhibitors Featuring an Acylhydrazone Scaffold with Potent Antileukemia Activity.

Journal of Medicinal Chemistry
Fat mass obesity-associated protein (FTO) has been emerging as a potential therapeutic target for drug discovery in RNA epigenetics. In this work, a series of novel FTO inhibitors featuring an acylhydrazone scaffold were identified, and the optimized ...
Xue-Wu Liang, Yue Huang, Hairu Ren, Qi Liu, Liang Chen, Jiayan Zhao, Xiangqian Gao, Jian Lu, Cai-guang Yang, Hong Liu   +9 more
semanticscholar   +1 more source

Additional file 3 of Evaluation of antiplasmodial activity in silico and in vitro of N-acylhydrazone derivatives

, 2022
Additional file 3: Figure SAH3.
Fernanda A. Oliveira (13027032), Eder Lorenzato Junior (13027041), Ana Claudia S. Pinto (13027035), Diogo T. Carvalho (4986722), Alex G. Taranto (7396214), Fernando P. Varotti (13027044), Amanda L. Fonseca (13027047), Caique L. Duarte (13027038), Cleydson Finotti Cordeiro (9502386)   +8 more
core   +1 more source

(5-Hydroxy-3-methyl-5-trifluoromethyl-4,5-dihydro-1H-pyrazol-1-yl)(2-hydroxyphenyl)methanone

IUCrData, 2016
In the title compound, C12H11F3N2O3, the hydroxyphenyl ring is twisted by 35.42 (11)° from the plane of the pyrazoline ring. The keto O atom is involved in two intramolecular O—H...O hydrogen bonds, which generate S(6) loops.
Kuvondik G. Avezov, Bako B. Umarov, Samat A. Talipov, Rishad J. Kunafiev, Bakhtiyar T. Ibragimov   +4 more
doaj   +1 more source

Dynamic Regulation of Proton and Water Transport through an Acylhydrazone-Based Photoresponsive Channel.

Journal of the American Chemical Society
Proton transport is crucial for cellular energy, and synthetic systems having the ability to control this process offer promising applications in drug development and cancer treatment.
Paras Wanjari, Ioan Stroia, A. van der Lee, Marc Baaden, Mihail Barboiu   +4 more
semanticscholar   +1 more source

NOESY experiment of N-acylhydrazone derivative LASSBio-1760 (2c).

, 2016
NOESY experiment of N-acylhydrazone derivative LASSBio-1760 (2c).
Natália M. Cordeiro (3167442), Carlos A. M. Fraga (128885), Patricia D. Fernandes (535868), Rosana H. C. N. Freitas (3167439)   +3 more
core   +1 more source