Advances in the Different Synthetic Routes of Fluorinated Hydrazines
The Chemical Record, EarlyView.This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
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N′-[(E)-4-Methylbenzylidene]pyridine-4-carbohydrazide monohydrate
IUCrData, 2016 In the title hydrate, C14H13N3O·H2O, the C=N double bond adopts an E conformation and the dihedral angle between the aromatic rings is 16.36 (10)°. In the crystal, N—H...O, O—H...O and O—H...N hydrogen bonds link the components into (001) sheets.
Wanda Pereira Almeida +2 more
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Materials & Design, 2021 The healing of diabetic foot ulcers (DFUs) is a major challenge for clinical treatment because of the hyperglycemic and acidic microenvironment in the wound area.
Zuhao Li +10 more
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Using a Non-Image-Based Medium-Throughput Assay for Screening Compounds Targeting N-myristoylation in Intracellular Leishmania Amastigotes [PDF]
, 2014 We have refined a medium-throughput assay to screen hit compounds for activity against N-myristoylation in intracellular amastigotes of Leishmania donovani. Using clinically-relevant stages of wild type parasites and an Alamar blue-based detection method,
A Misslitz +58 more
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Journal of Periodontal Research, EarlyView.Hydrogel‐based therapies have proven to be valuable tools to address the unique regeneration challenges of complex multi‐domain periodontal and craniofacial tissues. This review highlights and classifies clinically approved and emerging hydrogel therapies indicated for the regeneration of periodontal and craniofacial tissues.
Z. Gouveia +5 more
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A new series of acylhydrazones derived from metribuzin with modulated herbicidal activity
Heliyon, 2023 This paper reports the preparation and herbicidal evaluation of a small library of acylhydrazones based on the synthetic herbicide metribuzin. The hydrazone linkage easily obtained by reaction of metribuzin with aliphatic and aromatic aldehydes, masks ...
David Peña +8 more
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Biological and quantitative-SAR evaluations, and docking studies of (E)-N'-benzylidenebenzohydrazide analogues as potential antibacterial agents [PDF]
A series of 15 (E)-N'-benzylidenebenzohydrazide analogues were evaluated for their antimicrobial activities against eleven pathogenic and food-borne microbes, namely, S. aureus (G+), L. monocytogenes (G+), B. subtilis (G+), K.
Alam, Mohammad Sayed +4 more
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New synthetic routes to Triazolo-benzodiazepine analogues:expanding the scope of the bump-and-hole approach for selective Bromo and Extra-Terminal (BET) bromodomain inhibition [PDF]
, 2015 We describe new synthetic routes developed toward a range of substituted analogues of bromo and extra-terminal (BET) bromodomain inhibitors I-BET762/JQ1 based on the triazolo-benzodiazepine scaffold.
Alessio Ciulli +5 more
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Infrared Absorption Spectra of Acylhydrazone Derivatives
Nippon kagaku zassi, 1963 X-CO-NH-N=CH-Y骨格をもつ10種類のアシルヒドラゾン誘導体の赤外吸収スペクトルを臭化カリウム錠剤法により岩塩領域において測定した。これらのスペクトルを比較し,また類似物質から得られた振動数と比較検討することにより,つぎのように吸収帯の帰属を行なった。1650cm-1付近;アミド1吸収帯,1600cm-1付近;ベンゼン核面内骨格および>C=N-伸縮,1525cm-1付近;アミドII吸収帯,1500cm-1付近;ベンゼン核面内骨格,1435cm-1付近;-CH3逆対称変角,1368cm-1付近;-CH3対称変角,1290cm-1付近;アミド醗吸収帯,1184,1170cm-1付近;-N(CH3)2骨格,1230,1060,946cm-1付近;4-ジメチルアミノフェニレン基,818cm-1付近;
Kazuhisa MORIMOTO +2 more
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New N-acylhydrazones with Potential Cytotoxic Activity
Revista de Chimie, 2019 Some new N-acylhydrazones 7a-c having dibenzo[a,d][7]annulene moiety were synthesized by condensation of corresponding hydrazide 5 with aromatic aldehydes. The structures of these newly compounds were elucidated by IR, 1H-NMR, 13C-NMR, and elemental analysis.
Laura Ileana Socea +8 more
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