Results 71 to 80 of about 2,678 (221)

Synthesis of Novel N-Acylhydrazones and Their C-N/N-N Bond Conformational Characterization by NMR Spectroscopy [PDF]

open access: gold, 2021
Rubina Munir   +6 more
openalex   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Triazine‐Based Dual Histone Deacetylase/phosphatidylinositol 3‐kinase Inhibitors for Breast Cancer Therapy

open access: yesChemMedChem, Volume 21, Issue 8, 28 April 2026.
Breast cancer is the most frequently diagnosed malignancy and a leading cause of cancer‐related mortality among women worldwide. Triple‐negative breast cancer (TNBC) poses a major clinical challenge due to its aggressive nature, limited therapeutic options, and high propensity for drug resistance.
Lara Luzietti   +9 more
wiley   +1 more source

Color-tunable single-fluorophore supramolecular system with assembly-encoded emission

open access: yesNature Communications, 2020
Regulating fluorescent properties of small molecules in a controlled manner has been a fundamental research goal but realizing multi-color emission from a single fluorophore remains challenging.
Qian Wang   +7 more
doaj   +1 more source

Excimer Formation in Aqueous Solutions of Hosts and Application in Synthesis

open access: yesChemPhotoChem, Volume 10, Issue 4, April 2026.
This review explores how host‐mediated excimer formation in water, facilitated by supramolecular confinement enhances photochemical synthesis. By improving solubility, local concentrations, and orientational control, these systems can boost efficiency and selectivity in reactions like photocycloadditions and photodimerizations.
Doğan Akbulut   +3 more
wiley   +1 more source

Combination therapy of itraconazole and an acylhydrazone derivative (D13) for the treatment of sporotrichosis in cats

open access: yesMicrobiology Spectrum
Acylhydrazone (AH) derivatives represent a novel category of anti-fungal medications that exhibit potent activity against Sporothrix sp., both in vitro and in a murine model of sporotrichosis.
Isabella Dib Ferreira Gremião   +21 more
doaj   +1 more source

Antinociceptive and Cytotoxic Activity of Opioid Peptides with Hydrazone and Hydrazide Moieties at the C-Terminus

open access: yesMolecules, 2020
In the present contribution, we analyze the influence that C-terminal extension of short opioid peptide sequences by organic fragments has on receptor affinity, in vivo analgesic activity, and antimelanoma properties.
Jolanta Dyniewicz   +5 more
doaj   +1 more source

Toward Model Amphiphilic Polymer Co‐Networks: Linking Architecture to Structure and Properties

open access: yesMacromolecular Chemistry and Physics, Volume 227, Issue 7, 14 April 2026.
This review provides a comprehensive overview on model amphiphilic polymer co‐networks, demonstrating how precise control over network architecture enables systematic investigation of their structure and properties. By linking molecular design to macroscopic behavior, it highlights fundamental structure–property relationships and shows how these ...
Sebastian Seitel   +14 more
wiley   +1 more source

Infrared Absorption Spectra of Acylhydrazone Derivatives

open access: yesNippon kagaku zassi, 1963
X-CO-NH-N=CH-Y骨格をもつ10種類のアシルヒドラゾン誘導体の赤外吸収スペクトルを臭化カリウム錠剤法により岩塩領域において測定した。これらのスペクトルを比較し,また類似物質から得られた振動数と比較検討することにより,つぎのように吸収帯の帰属を行なった。1650cm-1付近;アミド1吸収帯,1600cm-1付近;ベンゼン核面内骨格および>C=N-伸縮,1525cm-1付近;アミドII吸収帯,1500cm-1付近;ベンゼン核面内骨格,1435cm-1付近;-CH3逆対称変角,1368cm-1付近;-CH3対称変角,1290cm-1付近;アミド醗吸収帯,1184,1170cm-1付近;-N(CH3)2骨格,1230,1060,946cm-1付近;4-ジメチルアミノフェニレン基,818cm-1付近;
Kazuhisa MORIMOTO   +2 more
openaire   +2 more sources

Design, synthesis, and evaluation of 4-chromenone derivatives combined with N-acylhydrazone for aurora kinase A inhibitor [PDF]

open access: gold, 2021
Soon Young Shin   +6 more
openalex   +1 more source

On‐Demand Chemically Degradable Hydrogels for Biological Applications

open access: yesChemBioChem, Volume 27, Issue 6, 27 March 2026.
This review explores the mechanisms and kinetics of chemically induced on‐demand degradation in hydrogels designed for painless dressing removal and traceless dissolution across various biological applications. Covalent bond cleavage and noncovalent disruption triggers are compared, highlighting opportunities for load‐bearing scaffolds with faster ...
Xinyi Sheng, Justin Kim
wiley   +1 more source

Home - About - Disclaimer - Privacy