Results 61 to 70 of about 508,769 (269)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Influence of lower-level reverse faults on shale gas enrichment and high yield: A case study of Pingqiao Dong-1 Fault in Nanchuan area, southeast margin of Sichuan Basin [PDF]

open access: yesYouqicang pingjia yu kaifa
Located in the complex structural area of the southeastern margin of Sichuan Basin, Nanchuan area is characterized by the prevalent development of low-level reverse faults.
GAO Quanfang,ZHANG Peixian,GUAN Linlin,LI Yanjing,NI Feng
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Reservoir-forming conditions of platform margin belt in southern slope of Tazhong, Tarim Basin

open access: yesPetroleum Exploration and Development, 2008
Based on the new seismic and logging data, this paper identifies the location and shape of the platform margin belt in Tazhong, Tarim Basin and studies its structural characteristics and reservoir-forming conditions using isochronous sequence framework ...
Zhi-qian GAO   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Formation and evolution of shale overpressure in deep Wufeng-Longmaxi Formation in southern Sichuan basin and its influence on reservoir pore characteristics

open access: yesFrontiers in Earth Science
In the deep Longmaxi Formation shale gas reservoirs of the southern Sichuan Basin, strong overpressure is universally developed to varying degrees. However, there is currently a lack of in-depth research on the formation mechanisms, evolutionary patterns,
Shasha Sun   +9 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Three-dimensional structural models, evolutions and petroleum geological significances of transtensional faults in the Ziyang area, central Sichuan Basin, SW China

open access: yesPetroleum Exploration and Development
With drilling and seismic data of Transtensional (strike-slip) Fault System in the Ziyang area of the central Sichuan Basin, SW China plane-section integrated structural interpretation, 3-D fault framework model building, fault throw analyzing, and ...
Fanglei TIAN   +8 more
doaj   +1 more source

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