Results 11 to 20 of about 39,851 (272)

Transcriptome differences between enrofloxacin-resistant and enrofloxacin-susceptible strains of Aeromonas hydrophila. [PDF]

PLoS ONE, 2017
Enrofloxacin is the most commonly used antibiotic to control diseases in aquatic animals caused by A. hydrophila. This study conducted de novo transcriptome sequencing and compared the global transcriptomes of enrofloxacin-resistant and enrofloxacin ...
Fengjiao Zhu, Zongying Yang, Yiliu Zhang, Kun Hu, Wenhong Fang   +4 more
doaj   +4 more sources

Fluoroquinolone-mediated inhibition of cell growth, S-G2/M cell cycle arrest, and apoptosis in canine osteosarcoma cell lines. [PDF]

, 2012
Despite significant advancements in osteosarcoma research, the overall survival of canine and human osteosarcoma patients has remained essentially static over the past 2 decades.
Chen, Xinbin, Holt, Roseline, Jung, Yong-Sam, Rebhun, Robert B, Rodriguez, Carlos O, Seo, Kyoung won   +5 more
core   +13 more sources

Enrofloxacin hydrochloride dihydrate [PDF]

Acta Crystallographica Section E Structure Reports Online, 2014
The asymmetric unit of the title compound, C19H23FN3O3+·Cl−·2H2O [systematic name: 4-(3-carboxy-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinolin-7-yl)-1-ethylpiperazin-1-ium chloride dihydrate], consists of two independent monocations of the protonated enrofloxacin, two chloride anions and four water molecules.
Jorge E. Miranda-Calderón, Lilia Gutiérrez, Marcos Flores-Alamo, Ponciano García-Gutiérrez, Héctor Sumano   +4 more
openaire   +3 more sources

Enrofloxacin—The Ruthless Killer of Eukaryotic Cells or the Last Hope in the Fight against Bacterial Infections?

International Journal of Molecular Sciences, 2022
Enrofloxacin is a compound that originates from a group of fluoroquinolones that is widely used in veterinary medicine as an antibacterial agent (this antibiotic is not approved for use as a drug in humans).
Łukasz Grabowski, Lidia Gaffke, Karolina Pierzynowska, Zuzanna Cyske, Marta Choszcz, G. Węgrzyn, A. Węgrzyn   +6 more
semanticscholar   +1 more source

Transcriptomics Analysis of the Toxicological Impact of Enrofloxacin in an Aquatic Environment on the Chinese Mitten Crab (Eriocheir sinensis)

International Journal of Environmental Research and Public Health, 2023
Enrofloxacin is an important antimicrobial drug that is widely used in aquaculture. Enrofloxacin residues can have negative effects on aquatic environments and animals.
Qiaona Wang, Ziling Xu, Ying Wang, Guangming Huo, Xing Zhang, Jianmei Li, C. Hua, Shengjie Li, F. Zhou   +8 more
semanticscholar   +1 more source

Effect of Enrofloxacin on the Microbiome, Metabolome, and Abundance of Antibiotic Resistance Genes in the Chicken Cecum

Microbiology spectrum, 2023
In this study, we investigated changes in the cecum flora, metabolites, and abundances of fluoroquinolone antibiotic resistance genes in chickens following the use of different concentrations of enrofloxacin.
Boheng Ma, De Wang, Xueran Mei, Changwei Lei, Cui Li, Hongning Wang   +5 more
semanticscholar   +1 more source

Blood creatinine content and rat kidney structure after intramuscular injection of pegylated antibiotic enrofloxacin

Біологічні студії, 2023
Background. Polyethylene glycol (PEG) is able to affect the permeability of memb­ra­nes by increasing the entry of antibiotics into the cell of microorganism; therefore, PEGylation may improve the effectiveness of antibiotics due to chemical modification
Mariia Kozak, Oksana Zelenina, Dmytro Ostapiv, Maryna Skrypka, Volodymyr Samaryk, Vasyl Vlizlo   +5 more
doaj   +1 more source

Population pharmacokinetic analysis of enrofloxacin and its active metabolite ciprofloxacin after intravenous injection to cats with reduced kidney function

Journal of Veterinary Internal Medicine, 2023
Background It is unknown if enrofloxacin accumulates in plasma of cats with reduced kidney function. Hypothesis To determine if enrofloxacin and its active metabolite ciprofloxacin have reduced clearance in azotemic cats.
Jonathan D. Foster, Mahmoud Abouraya, Mark G. Papich, Nancy A. Muma   +3 more
doaj   +1 more source

PK-PD integration of enrofloxacin and cefquinome alone and in combination against Klebsiella pneumoniae using an in vitro dynamic model

Frontiers in Pharmacology, 2023
Introduction:Klebsiella pneumoniae is classified as a critical pathogen in both animals and humans and infections can be fatal in chickens resulting in substantial economic losses. However, the misuse of antibiotics can also lead to drug resistance and a
Yanzhe Wei, Xuan Ji, Fuhui Zhang, Suiling Zhang, Qin Deng, Huanzhong Ding   +5 more
doaj   +1 more source

Enrofloxacin Induces Intestinal Microbiota-Mediated Immunosuppression in Zebrafish

Environmental Science and Technology, 2022
The immunosuppressive effects of antibiotics and the potential associations with the intestinal microbiota of the host have been increasingly recognized in recent years. However, the detailed underlying mechanisms of immune interference of antibiotics in
Wenhui Qiu, Tang Liu, Xinjie Liu, Honghong Chen, Shusheng Luo, Qiqing Chen, Jason T. Magnuson, C. Zheng, E. G. Xu, D. Schlenk   +9 more
semanticscholar   +1 more source