Results 191 to 200 of about 21,179 (232)
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LC determination of enrofloxacin
Journal of Pharmaceutical and Biomedical Analysis, 2002A simple, rapid and sensitive high-performance liquid chromatographic (HPLC) method was developed for the assay of enrofloxacin in raw material and injection. The validation method yielded good results and included the range, linearity, precision, accuracy, specificity, recovery, limit of detection (LOD) and limit quantification (LOQ) values.
Marinês J, e Souza +2 more
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Pharmacokinetics of enrofloxacin in turkeys
Research in Veterinary Science, 2007The pharmacokinetics of enrofloxacin (EFL) and its active metabolite ciprofloxacin (CIP) was investigated in 7-8 month old turkeys (6 birds per sex). EFL was administered intravenously (i.v.) and orally (p.o.) at a dose 10 mg kg(-1) body weight. Blood was taken prior to and at 0.17, 0.33, 0.5, 1, 2, 3, 4, 6, 8, 10 and 24 h following drug administration.
D J, Dimitrova +3 more
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Fate of Enrofloxacin in Swine Sewage
Journal of Agricultural and Food Chemistry, 2004The fate of enrofloxacin present in raw sewage at a swine-breeding facility was investigated by liquid-liquid extraction and reversed-phase liquid chromatography with photodiode array detection. Samples were collected in the storage pits of each pigsty and in a nonaerated lagoon used to stock the sewage.
PIERINI, ELISABETTA +3 more
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Nonlinear toxicokinetics of enrofloxacin in rats
Archives of Pharmacal Research, 2010The dose-dependent toxicokinetics of enrofloxacin were studied by administering various single subcutaneous doses (5, 10, 20, 40, 70, 100, 150, 200, 300 and 400 mg/kg) in male Sprague-Dawley rats. The blood samples were collected from the tail veins, and the plasma concentration of enrofloxacin was determined by an HPLC-fluorescence detection (FLD ...
Hee, Yi +9 more
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Effect of enrofloxacin on the proteome of earthworms
Science of The Total Environment, 2018The environmental and human health risks of veterinary drugs are becoming public health issues. Enrofloxacin (EF) is an extensively used animal-specific antibacterial agent that leaves drug residues in the environment. This study investigated the proteomic response of the earthworm Eisenia fetida to EF exposure. Earthworms were exposed to EF in soil at
Xiaoxu, Lu +7 more
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Pharmacokinetics of enrofloxacin in lactating sheep
Research in Veterinary Science, 2003The pharmacokinetics of enrofloxacin (ENR) was investigated after its intravenous (iv) and intramuscular (im) administration in six healthy lactating sheep. After iv ENR injection (as a bolus), the elimination half-life (t(1/2beta)), the volume of distribution (Vd(area)), and the area under the concentration vs. time curve (AUC) were 3.30 (0.36)h, 2.91
A, Haritova, L, Lashev, D, Pashov
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Pharmacokinetics of enrofloxacin in neonatal kittens
American Journal of Veterinary Research, 2004AbstractObjective—To determine the pharmacokinetics of enrofloxacin in neonatal kittens and compare the pharmacokinetics of enrofloxacin in young and adult cats.Animals—7 adult cats and 111 kittens (2 to 8 weeks old).Procedure—A single dose of 5 mg of enrofloxacin/kg was administered to adults (IV) and kittens (IV, SC, or PO).
M Alexis, Seguin +4 more
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Microbiological assay for enrofloxacin injection
International Journal of Pharmaceutics, 2004A simple, sensitive and specific agar diffusion bioassay for the antibacterial enrofloxacin was developed. Using a strain of Staphylococcus aureus ATCC 6538P as the test organism, enrofloxacin at concentrations ranging from 3.2 to 12.8 microg ml(-1) could be measured in injection. A prospective validation of the method showed that method was linear (r =
Marinês J, e Souza +2 more
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