Results 201 to 210 of about 21,179 (232)

Pharmacokinetic evaluation of enrofloxacin in chickens

British Poultry Science, 1997
1. The pharmacokinetics and bioavailability of enrofloxacin in chickens were investigated following intravenous, intramuscular, subcutaneous and oral administration of 10 mg/kg body weight. A rapid distribution phase was followed by a slower elimination phase. 2. The apparent volume of distribution was 2.2 l/kg.
M I, Abd el-Aziz, M A, Aziz, F A, Soliman, N A, Afify   +3 more
openaire   +2 more sources

Pharmacokinetic properties of enrofloxacin in rabbits

American Journal of Veterinary Research, 1991
SUMMARY The pharmacokinetic properties of the fluoroquinolone antimicrobial enrofloxacina were studied in New Zealand White rabbits. Four rabbits were each given enrofloxacin as a single 5 mg/kg of body weight dosage by iv, sc, and oral routes over 4 weeks. Serum antimicrobial concentrations were determined for 24 hours after dosing.
R L, Broome, D L, Brooks, J G, Babish, D D, Copeland, G M, Conzelman   +4 more
openaire   +2 more sources

Pharmacokinetics and residues of enrofloxacin in chickens

American Journal of Veterinary Research, 1995
Abstract The pharmacokinetic properties of enrofloxacin were determined in broiler chickens after single IV and orally administered doses of 10 mg/kg of body weight. After IV and oral administrations, the plasma concentration-time graph was characteristic of a two- compartment open model.
A, Anadón, M R, Martínez-Larrañaga, M J, Díaz, P, Bringas, M A, Martínez, M L, Fernàndez-Cruz, M C, Fernández, R, Fernández   +7 more
openaire   +2 more sources

Pharmacokinetics of Enrofloxacin and Its Metabolite Ciprofloxacin after Intramuscular Administration of Enrofloxacin in Goats

Veterinary Research Communications, 2001
The pharmacokinetics of enrofloxacin and its active metabolite ciprofloxacin were investigated in goats after a single intramuscular administration of enrofloxacin at 2.5 mg/kg body weight. The plasma concentrations of enrofloxacin and ciprofloxacin were determined simultaneously by a HPLC method.
G S, Rao, S, Ramesh, A H, Ahmad, H C, Tripathi, L D, Sharma, J K, Malik   +5 more
openaire   +2 more sources

Disposition kinetics of enrofloxacin and ciprofloxacin following intravenous administration of enrofloxacin in goats

Small Ruminant Research, 2002
Abstract Pharmacokinetic properties of the antimicrobial fluoroquinolone, enrofloxacin, were studied in female goats. Enrofloxacin was given to goats in a single dose of 2.5 mg kg −1 body weight by intravenous (i.v.) route. Blood samples were collected via jugular venipuncture into heparinized tubes at predetermined times after drug administration ...
G.S. Rao, S. Ramesh, A.H. Ahmad, H.C. Tripathi, L.D. Sharma, J.K. Malik   +5 more
openaire   +1 more source

Anti-enrofloxacin antibody production by using enrofloxacin-screened HSA as an immunogen

Journal of Ocean University of China, 2005
A two-step zero-length cross-linking procedure using active esters was successfully adopted for conjugating enrofloxacin (EF) to human serum albumin (HSA). The derived conjugate was characterized by UV spectrum and then used for immunization of BALB/C mice.
Chune Liu, Hong Lin, Limin Cao, Jie Jiang   +3 more
openaire   +1 more source

Pharmacokinetics of Enrofloxacin and its Metabolite Ciprofloxacin in Goats given Enrofloxacin Alone and in Combination with Probenecid

The Veterinary Journal, 2002
The pharmacokinetics of enrofloxacin and its active metabolite ciprofloxacin were investigated in goats given enrofloxacin alone or in combination with probenecid. Enrofloxacin was administered i.m. at a dosage of 5 mg x kg(-1) alone or in conjunction with probenecid (40 mg x kg(-1), i.v.).
G S, Rao, S, Ramesh, A H, Ahmad, H C, Tripathi, L D, Sharma, J K, Malik   +5 more
openaire   +2 more sources

Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and oral administration of enrofloxacin in dogs

Journal of Veterinary Pharmacology and Therapeutics, 1993
Rung, K., Riond, J.‐L. & Wanner, M. Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and oral administration of enrofloxacin in dogs. J. vetFour dogs were given 5 mg/kg body weight enrofloxacin intravenously (i.v.) and orally (p.o.) in a cross‐over study. Plasma concentrations of the active ingredient enrofloxacin
Küng K, Riond JL, Wanner M
openaire   +3 more sources

Placental transfer of enrofloxacin and ciprofloxacin in rabbits

American Journal of Veterinary Research, 1994
Summary Placental transfer of enrofloxacin and ciprofloxacin was evaluated, using a rabbit in situ perfusion model. A two-step infusion program was carried out to obtain steady-state maternal plasma concentrations of these drugs. For each compound, the placenta in 5 rabbits was perfused for 200 minutes with Earle's enriched bicarbonate buffer at flow ...
J J, Aramayona, M A, Garcia, L J, Fraile, A R, Abadía, M A, Bregante   +4 more
openaire   +2 more sources

Interaction of Enrofloxacin with Phospholipid Mono- and Bilayers

Langmuir, 1994
Peer ...
Mestres, Concepció, Alsina, M. Asunción, Busquets, Antonia, Haro Villar, Isabel, Reig Isart, Francisca   +4 more
openaire   +2 more sources