Results 51 to 60 of about 400,261 (171)

Land use gradients drive spatial variation in Lassa fever host communities in the Eastern Province of Sierra Leone

open access: yesJournal of Animal Ecology, Volume 95, Issue 2, Page 296-312, February 2026.
As West Africa urbanises, the risk of Lassa fever may paradoxically decrease. We found the invasive house mouse, a dominant urban species, outcompetes and displaces the primary Lassa virus host. Considering these species interactions is critical for accurately predicting future zoonotic disease patterns.
David Simons   +13 more
wiley   +1 more source

Avaliação da eficácia do artesunato associado à tetraciclina na terapêutica da malária falciparum

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 1997
Realizou-se um ensaio clínico, randomizado e controlado, comparando o artesunato com o quinino e a mefloquina, em casos de malária não grave. Foram tratados 42 pacientes em regime de internação e o seguimento durou 28 dias.
Villalobos Salcedo Juan Miguel   +4 more
doaj  

Evaluation of Chlorhexidine‐Containing Shampoos: In Vitro Efficacy Against Staphylococcus pseudintermedius and Lathering Ability

open access: yesVeterinary Dermatology, Volume 37, Issue 1, Page 148-160, February 2026.
Background: The antibacterial efficacy of chlorhexidine shampoo is directly affected by formulation and bathing factors. Hypothesis/Objective: To evaluate the in vitro antibacterial efficacy of chlorhexidine‐containing shampoos at various dilutions and to compare their lathering ability.
Emily E. Binversie   +2 more
wiley   +1 more source

Ensaio clínico com um novo anti-epiléptico (barbexaclone)

open access: yesArquivos de Neuro-Psiquiatria, 1977
Foi experimentado um novo anti-epiléptico (barbexaclone) em 48 pacientes que apresentavam 67 tipos de crises, destacando-se o fato de que todos eram casos considerados maus, seja pela intensidade das manifestações epilépticas, seja para refratariedade a ...
José Hermínio Bragatti   +2 more
doaj   +1 more source

Representações sociais de crianças participantes de um ensaio clínico sobre o pesquisador: de detentor do saber à criança curiosa

open access: yesSaúde e Sociedade, 2014
Intervenções educativas constituem importantes ferramentas para a ampliação do conhecimento científico e em ensaios clínicos devem contribuir para a tomada de decisão quanto à participação na pesquisa.
Maria Flávia Carvalho Gazzinelli   +6 more
doaj   +1 more source

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source

Ensaio clínico randomizado [PDF]

open access: yes, 2012
Exemplo de Ensaio Clínco ...
Stein, Airton
core  

Model‐based evaluation of the interaction between ritonavir‐boosted atazanavir and rifampicin in Ugandan adults with HIV

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 12, Page 3471-3481, December 2025.
Aim Concomitant treatment of tuberculosis (TB) and human immunodeficiency virus (HIV) is complicated by drug‐drug interactions (DDI). This analysis aimed to characterize the DDI between ritonavir‐boosted atazanavir (ATV/r) and rifampicin in plasma and peripheral blood mononuclear cells (PBMC).
Allan Kengo   +10 more
wiley   +1 more source

Intervenções para cuidadores de sobreviventes de acidente vascular cerebral: revisão sistemática

open access: yesRevista Panamericana de Salud Pública, 2018
Objetivo. Sintetizar e criticar a produção científica sobre as intervenções desenvolvidas para reverter a sobrecarga de cuidado e os fatores associados em cuidadores de sobreviventes de acidente vascular cerebral (AVC). Método.
Jaine Kareny da Silva   +5 more
doaj   +1 more source

New Evidence of TLR4 and TLR9 Variants Influencing Parasitaemia and Symptoms of Plasmodium vivax Infection

open access: yesInternational Journal of Immunogenetics, Volume 52, Issue 6, Page 371-378, December 2025.
ABSTRACT Toll‐like receptors (TLRs) induce the production of pro‐inflammatory cytokines and regulate the immune response to Plasmodium vivax infection. Genetic variants of TLRs are associated with susceptibility and severity of malaria in different populations. This study aimed to evaluate the association between polymorphisms in TLR1, TLR4, TLR7, TLR8,
Mikaele Monik Rodrigues Inácio Silva   +8 more
wiley   +1 more source

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