Results 51 to 60 of about 13,747 (168)

Experiência em Ensaios Clínicos na Empresa Novartis [PDF]

, 2020
Este projeto foi desenvolvido no âmbito da 1ª edição do Mestrado em Gestão da Investigação Clínica (MEGIC) que surge da colaboração entre a Universidade NOVA de Lisboa (Nova Medical School | Faculdade de Ciências Médicas (NMS |FCM), NOVA Information ...
Sousa, Susana Maria de Oliveira
core  

Evidences That Host Genetic Background More Than the Environment Shapes the Microbiota of the Snail Bulinus truncatus, an Intermediate Host of Schistosoma Species

Molecular Ecology, Volume 35, Issue 6, March 2026.
ABSTRACT Microbiota have emerged as fundamental regulators of host physiology, shaping both ecological interactions and evolutionary trajectories. Yet, the determinants of microbiota diversity and structure in wild populations—particularly the respective roles of host genetics and environmental context—are still poorly understood.
Mathilde J. Jaquet, Philippe Douchet, Eve Toulza, Thierry Lefevre, Bruno Senghor, Jérôme Boissier, Olivier Lepais, Emilie Chancerel, Benjamin Gourbal, Olivier Rey   +9 more
wiley   +1 more source

Diagnostic Concordance of Two‐ and Three‐Gene SARS‐CoV‐2 Molecular Assays in Cameroon: Implications for Efficient Pandemic Response in Low‐ and Middle‐Income Countries

Journal of Clinical Laboratory Analysis, Volume 40, Issue 4, February 2026.
This study assessed the interoperability of DaAn Gene, ThermoFisher, and GeneXpert assays used for COVID‐19 testing in Cameroon. GeneXpert showed higher diagnostic performance over ThermoFisher, with all assays having excellent agreement at high viral loads (CT < 20).
Aurelie Minelle Kengni Ngueko, Sandrine Claire Djupsa Ndjeyep, Ezechiel Ngoufack Jagni Semengue, Alex Durand Nka, Collins Ambe Chenwi, Aude Christelle Ka'e, Yagai Bouba, Jeremiah Efakika Gabisa, Evariste Molimbou, Naomi‐Karell Etame, Tatiana Anim‐Keng Tekoh, Rachel Audrey Nayang Mundo, Pamela Patricia Tueguem, Vincent Kamael Mekel, Hugues Mba, Désiré Takou, Grace Angong Beloumou, Michel Carlos Tommo Tchouaket, Larissa Gaelle Moko Fotso, Derrick Tambe Ayuk, Christian Ngongang Ouankou, Claudia Alteri, Luna Colagrossi, Yap Boum II, Halle Gregory Eddy Ekane, Francesca Ceccherini‐Silberstein, Vittorio Colizzi, Nicaise Ndembi, Alfred K. Njamnshi, Alexis Ndjolo, Carlo‐Federico Perno, Maria‐Mercedes Santoro, Joseph Fokam   +32 more
wiley   +1 more source

Land use gradients drive spatial variation in Lassa fever host communities in the Eastern Province of Sierra Leone

Journal of Animal Ecology, Volume 95, Issue 2, Page 296-312, February 2026.
As West Africa urbanises, the risk of Lassa fever may paradoxically decrease. We found the invasive house mouse, a dominant urban species, outcompetes and displaces the primary Lassa virus host. Considering these species interactions is critical for accurately predicting future zoonotic disease patterns.
David Simons, Rory Gibb, Umaru Bangura, Dianah Sondufu, Joyce Lamin, James Koninga, Momoh Foday, Mike Dawson, Joseph Lahai, Rashid Ansumana, Elisabeth Fichet‐Calvet, Deborah Watson‐Jones, Richard Kock, Kate E. Jones   +13 more
wiley   +1 more source

A pandemia tem estimulado o interesse global em melhorar a implementação de ensaios clínicos. [PDF]

, 2022
Discute a necessidade de encontrar soluções para os problemas de saúde que afetam a população mundial, e à percepção de que a pandemia estimulou muitos ensaios clínicos, mas a grande maioria não foi suficientemente grande para fornecer resultados ...
Salud y Fármacos
core   +1 more source

Estágio em coordenação de ensaios clínicos [PDF]

, 2014
Mestrado em Biomedicina FarmacêuticaThis report concerns my internship experience in the Clinical Neuropharmacology Group of Neurological Clinical Research Unit, where I could work in coordination of clinical trials, and in the Laboratory of Clinical ...
Barra, Márcio Correia
core   +3 more sources

Evaluation of Chlorhexidine‐Containing Shampoos: In Vitro Efficacy Against Staphylococcus pseudintermedius and Lathering Ability

Veterinary Dermatology, Volume 37, Issue 1, Page 148-160, February 2026.
Background: The antibacterial efficacy of chlorhexidine shampoo is directly affected by formulation and bathing factors. Hypothesis/Objective: To evaluate the in vitro antibacterial efficacy of chlorhexidine‐containing shampoos at various dilutions and to compare their lathering ability.
Emily E. Binversie, Jason B. Pieper, Darren J. Berger   +2 more
wiley   +1 more source

Ensaios Clínicos em Medicamentos [PDF]

, 2013
Randomized controlled trial, despite some disadvantages, is usually considered the gold standard for determining the efficacy of an intervention (drugs, clinical devices, surgery, etc.). In this article, we discuss some aspects of the trial design needed
Borges, Margarida
core   +1 more source

Intervenção de esportes modificados para melhorar metas de participação e competências de atividade em crianças deambuladoras com paralisia cerebral: um ensaio clínico randomizado

Developmental Medicine &Child Neurology, Volume 68, Issue 1, Page e1-e15, January 2026.
Intervenções de esportes modificados para crianças com Paralisia Cerebral: Resumo gráfico. Resumo Objetivo Avaliar a eficácia de uma intervenção de esportes modificados (Sports Stars Brasil) nos objetivos de participação em atividades físicas de lazer, desempenho e capacidade motora, funções corporais, níveis de atividade física, alfabetização física e
Ricardo R. Sousa Junior, Georgina L. Clutterbuck, Rafaela F. Guimaraes, Mariane G. Souza, Luana C. Silva, F. Virginia Wright, Ana Cristina R. Camargos, Hércules R. Leite   +7 more
wiley   +1 more source

Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Controlled Human Infection Models (CHIMs) offer a powerful approach to accelerate vaccine development for neglected tropical diseases (NTDs). This review highlights scientific and translational advances enabled by CHIMs, with a focus on a novel Leishmania major model.
Vivak Parkash
wiley   +1 more source