Results 71 to 80 of about 1,759,415 (331)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Phi_0 - Periodic Aharonov-Bohm Oscillations Survive Ensemble Averaging
, 1993 We have demonstrated that Phi_0 periodic Aharonov--Bohm oscillations measured in a ensemble of rings may survive after ensemble averaging procedure. The central point is the difference between the preparation stage of the ensemble and the subsequent ...
A. Altland +14 more
core +1 more source
Stepwise Amplification of Circularly Polarized Luminescence in Chiral Metal Cluster Ensembles [PDF]
, 2023 Jia‐Yin Wang +8 more
openalex +1 more source
Nucleic Acids Research, 2010 The Ensembl project (http://www.ensembl.org) seeks to enable genomic science by providing high quality, integrated annotation on chordate and selected eukaryotic genomes within a consistent and accessible infrastructure. All supported species include comprehensive, evidence-based gene annotations and a selected set of genomes includes additional data ...
Flicek, Paul +51 more
openaire +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
GENESIM : genetic extraction of a single, interpretable model [PDF]
, 2016 Models obtained by decision tree induction techniques excel in being interpretable.However, they can be prone to overfitting, which results in a low predictive performance. Ensemble techniques are able to achieve a higher accuracy. However, this comes at
De Turck, Filip +4 more
core +2 more sources
Probabilistic temperature forecasting based on an ensemble AR modification
, 2015 To address the uncertainty in outputs of numerical weather prediction (NWP) models, ensembles of forecasts are used. To obtain such an ensemble of forecasts the NWP model is run multiple times, each time with different formulations and/or initial or ...
Groß, Jürgen, Möller, Annette
core +1 more source
Global Ionospheric TEC Forecasting for Geomagnetic Storm Time Using a Deep Learning‐Based Multi‐Model Ensemble Method [PDF]
, 2023 Xiaodong Ren +5 more
openalex +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Multimodal Technologies and Interaction, 2020 The exigency of emotion recognition is pushing the envelope for meticulous strategies of discerning actual emotions through the use of superior multimodal techniques.
Mohammad Faridul Haque Siddiqui +1 more
doaj +1 more source