Results 1 to 10 of about 3,231 (133)

Biochemical Characterization of a Kunitz-Type Protease Inhibitor From Mimosa regnellii and Its Effects on Melanoma Cell Viability and Angiogenesis. [PDF]

Chem Biodivers
A Kunitz‐type serine protease inhibitor (JTI) purified from Mimosa regnellii seeds selectively targets melanoma cells. JTI triggers mitochondrial apoptosis, increases ROS and Ca2+ levels, arrests the cell cycle, and suppresses migration and angiogenesis without affecting healthy cells.
Rabêlo LMA, Cardoso PHO, Nobre LTDB, Dos Santos PIM, Lucena SV, Serquiz RP, Bemquerer MP, Rocha HAO, Nader HB, Dos Santos EA, de Oliveira AS, Frihling BEF, Migliolo L.   +12 more
europepmc   +2 more sources

Urine-Derived iPSC Neurospheres Uncover Proteomic Correlates of Clinical Severity in Dravet Syndrome. [PDF]

J Neurochem
Urine epithelial cells from Dravet syndrome (DS) patients carrying distinct SCN1A variants were reprogrammed into induced pluripotent stem cells (iPSCs) and differentiated into neural stem cells (NSCs) to generate patient‐derived neurospheres. Three neurosphere lines were analyzed in biological triplicates using isobaric quantitative proteomics ...
Martins M, Nugue G, Aguiar A, Souza LRQ, Abrantes PV, Trajano JR, Stelling M, Junqueira M, Rehen S, Guimarães MZP.   +9 more
europepmc   +2 more sources

Homogalacturonan From Yellow Passion Fruit Peel Ameliorates Intestinal Injury in DSS-Induced Colitis in Mice. [PDF]

J Cell Mol Med
ABSTRACT Ulcerative colitis is a chronic inflammatory bowel disease characterised by persistent inflammation of the colonic mucosa. Symptoms include bloody diarrhoea and abdominal pain, which have a significant impact on quality of life. Current treatments mainly alleviate symptoms and maintain remission, but natural therapeutic alternatives are still ...
Mazeti SSS, Turini AA, Bueno LR, Lima CD, Bastos RS, Rocha JA, Cordeiro LMC, Maria-Ferreira D, Gois MB.   +8 more
europepmc   +2 more sources

PCPDTBT Conjugated Polymer Nanoparticles for Photothermal Inactivation of Multidrug-Resistant <i>mcr‑1</i>-Positive <i>Escherichia coli</i>. [PDF]

ACS Omega
Caires CSA, Nascimento RC, Araujo LO, Aguilera LF, Oliveira SL, Caires ARL.   +5 more
europepmc   +1 more source

Niobium-Decorated Multiwalled Carbon Nanotubes for Voltammetric Detection of Paracetamol. [PDF]

ACS Omega
de Oliveira RH, da Silva MM, de Carvalho CT, Gonçalves DA, Dos Reis DD.   +4 more
europepmc   +1 more source

A New Method for Predicting the Liquid Dynamic Viscosity of Biodiesel-Related Esters Based on the Corresponding State Principle. [PDF]

ACS Omega
da Silva MRL, Alves AAA, Evangelista NS, Melo RLF, do Carmo FR, Chiavone-Filho O.   +5 more
europepmc   +1 more source

Fluorinated Solvents for Chemoselective Oxidations: A Strategy toward Synthetic Ideality in Natural Product Synthesis. [PDF]

ACS Org Inorg Au
Santana VCS, Gonçalves LDP, Salmazo YN, Pavan JCS, de A Simoni D, Heleno VCG, de Lucca EC.   +6 more
europepmc   +1 more source

In Silico Approach for Early Antimalarial Drug Discovery: De Novo Design of Virtual Multi-Strain Antiplasmodial Inhibitors. [PDF]

Microorganisms
Kleandrova VV, Cordeiro MNDS, Speck-Planche A.   +2 more
europepmc   +1 more source