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The immunopathogenesis of Entamoeba histolytica
Experimental Parasitology, 2010Amebiasis is the disease caused by the enteric dwelling protozoan parasite Entamoeba histolytica. The WHO considers amebiasis as one of the major health problems in developing countries; it is surpassed by only malaria and schistosomiasis for death caused by parasitic infection. E.
Leanne Mortimer, Kris Chadee
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Introns of Entamoeba histolytica and Entamoeba dispar
Protist, 2001The genome of Entamoeba histolytica is considered to possess very few intervening sequences (introns), as only 5 intron-containing genes from this protozoan parasite have been reported so far. However, while sequencing a number of genomic contigs as well as three independent genes coding for ribosomal protein L27a, we have identified 9 additional ...
Ute Willhoeft+4 more
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Cytopathogenicity of Entamoeba histolytica
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1984The lesions induced in man by Entamoeba histolytica are characterized by massive tissue injury in the absence of major local signs of a host immune response. The amoeba damages surrounding cells preferentially by contact-mediated cytolysis. Recently, a presumptive aetiological factor underlying this process has been
Edna Calef, Carlos Gitler, I. Rosenberg
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2004
Publisher Summary This chapter discusses Entamoeba histolytica, basic microbiology, origin and taxonomy, metabolism and physiology, clinical features, pathogenicity and virulence, treatment, survival in the environment, methods of detection, epidemiology of waterborne outbreaks, and finally, risk assessment.
Steven Percival+5 more
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Publisher Summary This chapter discusses Entamoeba histolytica, basic microbiology, origin and taxonomy, metabolism and physiology, clinical features, pathogenicity and virulence, treatment, survival in the environment, methods of detection, epidemiology of waterborne outbreaks, and finally, risk assessment.
Steven Percival+5 more
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Size Variation in Entamoeba histolytica
Nature, 1958THE human bowel is inhabited by amoebae with the morphology of Entamoeba histolytica, but of differing mean size. The larger of these can be tissue-invading pathogens or may, usually in a smaller form, remain as a commensal in the bowel1. Further, there is considerable overlap in size range, at least in the commensal form, with a still smaller amoeba ...
L. Freedman, R. Elsdon-Dew
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Purine Salvage in Entamoeba histolytica
The Journal of Parasitology, 1985Pulse-labeling of the nucleotide pool in Entamoeba histolytica with radioactive precursors, and subsequent high performance liquid chromatographic (HPLC) analysis of the radiolabeled nucleotides, indicate that E. histolytica is incapable of de novo synthesis of purine nucleotides. Hypoxanthine, inosine and xanthine could not be converted to nucleotides
Hsin-Sheng Lo, C. C. Wang
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Immunocytochemical detection of Entamoeba histolytica
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987Human anti-Entamoeba histolytica immunoglobulin was used to detect Entamoeba histolytica in 74 positive samples from several different sources, using an indirect immunoperoxidase method. In 73 samples, the protozoan was easily identified. Trophozoites and cysts of all cultured Entamoeba strains examined were strongly stained, and as few as 3 ...
Gladys Perozo-Ruggeri+5 more
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MCM Proteins of Entamoeba histolytica
Archives of Medical Research, 2000A majority of eukaryotes have developed an intricate machinery for precisely replicating their genome only once per cell cycle. DNA reduplication is not permitted until mitosis has been completed. Several factors essential for the regulation of intiation of DNA replication have been identified, such as the hexameric origin recognition complex (ORC ...
Anuradha Lohia, Suchismita Das
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The electrophoretic karyotype of Entamoeba histolytica
Molecular and Biochemical Parasitology, 1999Although knowledge about gene organization and transcription control in the protozoan parasite Entamoeba histolytica has increased substantially during the last few years, questions remain open about ploidy, organization and number of chromosomes in this human pathogen.
Egbert Tannich, Ute Willhoeft
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