Results 71 to 80 of about 27,459 (304)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Enteral administration of the protease inhibitor gabexate mesilate preserves vascular function in experimental trauma/hemorrhagic shock. [PDF]

Sci Rep, 2023
J D Moreira N, Dos Santos F, Li JB, Aletti F, Irigoyen MCC, Kistler EB.   +5 more
europepmc   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Unraveling medication errors in enteral tube administration: A cross-sectional study in geriatric patients receiving home health care

Saudi Pharmaceutical Journal
Background: Medication administration through enteral feeding tubes requires careful consideration, as several medications are unsuitable for such administration due to interactions with feeding formulas or adverse effects when crushed.
Nisrin Bifari, Ibtihaj N. Bifari, Yusuf Ahmed Alharbi   +2 more
doaj  

Microbiological Quality of Commercial Enteral Feedings used in Two Public Hospitals in Shiraz, Iran [PDF]

Journal of Health Sciences and Surveillance System, 2014
Background: Although enteral feeding solutions are used to reduce the morbidity and mortality in many malnourished and hospitalized patients, microbial contamination of these products may lead to severe infections, especially in immune suppressed ones ...
Mahsa Moazen, Samane Rahmdel, Seyedeh Maryam Abdollahzadeh, Maryam Ranjbar Zahedani, Seyed Mohammad Mazloomi   +4 more
doaj  

Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction. [PDF]

Proc Natl Acad Sci U S A, 2022
Reizine F, Grégoire M, Lesouhaitier M, Coirier V, Gauthier J, Delaloy C, Dessauge E, Creusat F, Uhel F, Gacouin A, Dessauge F, Le Naoures C, Moreau C, Bendavid C, Daniel Y, Petitjean K, Bordeau V, Lamaison C, Piau C, Cattoir V, Roussel M, Fromenty B, Michelet C, Le Tulzo Y, Zmijewski J, Thibault R, Cogné M, Tarte K, Tadié JM.   +28 more
europepmc   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Enteral administration of alectinib for ALK-positive non-small cell lung cancer in an elderly patient: A case report. [PDF]

Medicine (Baltimore), 2021
Thomas QD, Pautas M, Guilhaume MN, Fiteni F, Ge T, Girard N.   +5 more
europepmc   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

In Vivo Study of Entero- and Hepatotoxicity of Silver Nanoparticles Stabilized with Benzyldimethyl-[3-myristoylamine)-propyl]ammonium Chloride (Miramistin) to CBF1 Mice upon Enteral Administration. [PDF]

Nanomaterials (Basel), 2021
Krutyakov YA, Kudrinskiy AA, Kuzmin VA, Pyee J, Gusev AA, Vasyukova IA, Zakharova OV, Lisichkin GV.   +7 more
europepmc   +1 more source