Results 41 to 50 of about 99,078 (337)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Cognitive influencing factors of ICU nurses on enteral nutrition interruption: a mixed methods study

BMC Nursing
Background The incidence of clinically avoidable enteral nutrition interruptions is high. ICU nurses, as the implementers and monitors of enteral nutrition, have a close relationship between their cognitive level of enteral nutrition interruption and the
Huiling Pan, Chuanlai Zhang, Ruiqi Yang, Peng Tian, Jie Song, Zonghong Zhang   +5 more
doaj   +1 more source

Early outcomes of gastrostomy feeding in paediatric allogenic bone marrow transplantation: A retrospective cohort study [PDF]

, 2019
Background: Nutrition support is an essential component of care for a child undergoing bone marrow transplantation (BMT). Enteral nutrition (EN) is becoming increasingly recognised as having advantages over parenteral nutrition (PN) and recommended as ...
Andersen, Arends, August, Azarnoush, Barron, Baumgartner, Bicakli, Cohen, Cole, Department of Health, Fuji, Fuji, Gonzales, Hastings, Haupt, Heimfeld, Hopman, Iestra, Kaur, Kim, Kudsk, Langdana, Lemal, Lipkin, Montgomery, Moore, Murray, Papadopoulou, Papadopoulou, Pedersen, Przepiorka, Sureda, Thompson, Walrath, White, Yilmaz   +35 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Feeding: the hidden variable affecting prognosis of critically ill children

Egyptian Pediatric Association Gazette, 2022
Background Nutrition of critically ill children is a frequently ignored issue. The purpose of this study was to describe nutritional practices in the pediatric intensive care unit (PICU) in a resource-limited country and evaluate their association with ...
Muhammad Said El-Mekkawy, Gamal Ibrahim Shabaan, Alyaa Ahdy Abdelaziz   +2 more
doaj   +1 more source

Comparación entre nutrición enteral precoz y nutrición enteral tardía en el estado nutricional de pacientes gastrectomizados [PDF]

, 2009
Indexación: ScieloLa nutrición enteral (NE) es un método efectivo para cubrir los requerimientos nutricionales en pacientes que presentan un estado nutricional deteriorado.
Aranda Ch., Waldo, Campano B, Mónica, Kehr S, Juan, Morales V., Blanca, Rosales B., Valeria   +4 more
core  

SCAMP:standardised, concentrated, additional macronutrients, parenteral nutrition in very preterm infants: a phase IV randomised, controlled exploratory study of macronutrient intake, growth and other aspects of neonatal care [PDF]

, 2011
Background Infants born
A Dinerstein, A Grover, A Ogilvy-Stuart, A Riskin, AM Dusick, Anna Hart, B Koletzko, BB Poindexter, BE Stephens, BT Bloom, C Beecroft, C Fusch, C Morgan, Colin Morgan, CT Collins, DC Wilson, DG Mason, DM Hans, EKM Stoltz Sjöström, FWJ te Braake, FWJ te Braake, HM Ibrahim, IE Olsen, Isam Badhawi, JD Johnson, JE Dice, K Kotsopoulos, Kelly Mayes, M Ahmed, M Hack, M Hack, M Skouroliakou, MA Berry, MA Puago, Mark A Turner, Maw Tan, MJ Tan, MJ Tan, MY Yeung, N Murdock, NE Embleton, NS Wood, NS Wood, P Jadhav, PA Ball, Paul Newland, PJ Porcelli Jr, PJ Thureen, PJ Thureen, PJ Thureen, R Donovan, R Lenclen, RA Ehrenkranz, RA Ehrenkranz, RH Clark, RH Clark, RH Clarke, RJ Cooke, RW Cooke, RW Cooke, RW Cooke, S Eleni-dit-Trolli, S Kashyap, S Keady, SC Hartwig, Shakeel Herwitker, T Smolkin   +66 more
core   +3 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Association between early enteral nutrition and 28-Day mortality in mechanically ventilated patients with sepsis: a retrospective analysis of the MIMIC-IV database

BMC Infectious Diseases
Background The optimal timing of enteral nutrition for critically ill septic patients in the intensive care unit (ICU) who require invasive mechanical ventilation has not been determined, and the influence of early enteral nutrition on clinical outcomes ...
Fuchao Xu, Geng Lu, Hao Sun, Jun Wang
doaj   +1 more source