Results 211 to 220 of about 8,350 (244)

Population pharmacokinetics and IVIVC for mesalazine enteric-coated tablets

Journal of Controlled Release, 2022
Although in-vivo bioequivalence (BE) study serves as a golden standard for establishing interchangeability of oral dosage forms, it remains challenging for products with high inter-subject variability such as mesalazine enteric-coated tablet to fulfil the BE criteria set by regulatory authorities.
Yufeng, Zhang, Siu Kwan, Wo, Wei, Leng, Fang, Gao, Xiaoyu, Yan, Zhong, Zuo   +5 more
openaire   +2 more sources

GLC Determination of Erythromycin in Enteric-coated Tablets

Journal of Pharmaceutical Sciences, 1972
A GLC assay method for erythromycin in tablets is described. This method involves the extraction, silylation, and chromatography of erythromycin from tablets, and it yields an average recovery of 100.6% with a coefficient of variation of about 2%.
John H. Robertson, Kiyoshi Tsuji
openaire   +3 more sources

Development and Evaluation of Enteric-Coated Penicillamine Tablets

Journal of Pharmaceutical Sciences, 1984
Commercially available 250-mg penicillamine tablets were converted into enteric-coated tablets. Based on in vitro dissolution and disintegration tests, tablets coated with five layers of a cellulose acetate phthalate formulation by a modified pan coating technique were judged to be superior to other coated tablets. These tablets resisted disintegration
Diana A. Chambliss, Arthur H. Kibbe, Alan B. Jones, Ernest C. Harland, Walter G. Chambliss, Robert W. Cleary   +5 more
openaire   +3 more sources

Kinetics of release from enteric-coated tablets.

Pharmaceutical research, 1988
Controlled and localized release of drugs in the intestine can be achieved by enteric coating. The design of enteric-coated tablets has so far remained empirical, in part because of the lack of a quantitative description of the drug release kinetics. In this paper, a mathematical model is presented that describes the dissolution of the polymer coating ...
Palsson, Bernhard Ø, Dressman, Jennifer B., Donohoe, Bruce, Ozturk, Sadettin S.   +3 more
openaire   +4 more sources

Comparison of the Gastrointestinal Side Effects of Naproxen Formulated as Plain Tablets, Enteric-Coated Tablets, Or Enteric-Coated Granules in Capsules

Scandinavian Journal of Gastroenterology, 1989
We studied the gastrointestinal side effects of three formulations of naproxen in 18 healthy male volunteers. In a Latin-square design crossover study, the subjects received 500 mg naproxen twice daily for 7 days as plain tablets, enteric-coated tablets, or enteric-coated granules in capsules.
S. Larsen, M. Osnes, Lars Aabakken, B. A. Bjørnbeth, B. Olaussen, B. Hofstad   +5 more
openaire   +3 more sources

Compression of enteric-coated pellets to disintegrating tablets

International Journal of Pharmaceutics, 1996
Abstract Enteric-coated sucrose pellets containing a layer of bisacodyl beneath the coating were compressed into tablets on an instrumented single-punch machine using four different filler-binders for direct compression. Different copolymers based on polymethacrylates were applied as coatings.
Klaus Dr Lehmann, Thomas E. Beckert, Peter C. Schmidt   +2 more
openaire   +2 more sources

Gastric Retention of Enteric-Coated Magnesium Chloride Tablets

Annals of Pharmacotherapy, 1994
OBJECTIVE: To describe a patient with gastric retention of enteric-coated magnesium chloride tablets. Potential drug and disease etiologies accounting for failure to empty this dosage form are discussed. DESIGN: Single case report. CASE SUMMARY: A seriously ill patient with metastatic small-cell lung cancer accumulated 21 enteric-coated magnesium ...
Lisa B. Korman, Dennis J. Chapron, William L. Barry   +2 more
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Absorption and Metabolism of Aspirin Administered in Enteric-Coated Tablets

JAMA: The Journal of the American Medical Association, 1965
Variations in the absorption pattern of aspirin in enteric-coated tablets and in solution were compared between subjects and between doses in any one subject. Absorption of enteric-coated tablets was complete but the rate was extremely variable. On the other hand, administration of aspirin in solution was not only complete, but also yielded well ...
Jack R. Leonards, Gerhard Levy
openaire   +3 more sources

Crushed Enteric-Coated Methenamine Tablets

JAMA: The Journal of the American Medical Association, 1973
To the Editor.— The authors of the article, "Lipoid Pneumonia Caused By Methenamine Mandelate Suspension" (225:1524, 1973), concluded that "Simply, methenamine tablets can be crushed and given with food to problem patients." Methenamine mandelate (Mandelamine) is available as an entericcoated tablet (0.25, 0.5, 1.0 gm).
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Dissolution Behavior of Commercial Enteric-coated Aspirin Tablets

Journal of Pharmaceutical Sciences, 1979
Dissolution behavior was studied for four commercial batches of enteric-coated aspirin tablets from two companies. The USP XIX dissolution procedure was modified by including pretreatment in simulated gastric juice. The effects of five pretreatment times were studied.
Koral Embil, George Torosian
openaire   +3 more sources