Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti +19 more
wiley +1 more source
Tachykinin signaling defines distinct populations of glia in the enteric nervous system. [PDF]
Muppirala AN +12 more
europepmc +1 more source
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette +13 more
wiley +1 more source
Magnitude, resistance profiles, and risk factors of intestinal parasites and enteric bacteria among food handlers in West Guji Zone, Ethiopia. [PDF]
Asefa L +7 more
europepmc +1 more source
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source
Morphological evidence suggestive of a hierarchical mode of glial cell diversification and intrinsic developmental plasticity within the murine enteric nervous system. [PDF]
Lefèvre MA +3 more
europepmc +1 more source
Enteric Duplication Cysts as a Diagnostic and Therapeutic Challenge: Three Unique Case Reports With Review of Literature. [PDF]
Reddy YSB +6 more
europepmc +1 more source
CDX2 Expression and Fluoropyrimidine Response in Rare Non-GI Tumors: A Three-Case Series. [PDF]
Suleiman R +4 more
europepmc +1 more source
Salivary Varicella Zoster Virus DNA Detection in Patients With Acute Abdominal Pain: Frequency, Diagnostic Value, and Implications for Enteric Zoster. [PDF]
Son HJ +5 more
europepmc +1 more source

