Results 261 to 270 of about 45,406 (281)
Antithrombin: Deficiency, Diversity, and the Future of Diagnostics
ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt+2 more
wiley +1 more source
Safety and Effect of 12‐Month Ecopipam Treatment in Pediatric Patients with Tourette Syndrome
Abstract Background Tourette syndrome (TS) is a chronic neurodevelopmental tic disorder with a considerable quality of life (QOL) burden. Objectives The goal was to determine the long‐term safety, tolerability, and clinical effects of ecopipam, a first‐in‐class dopamine D1 receptor antagonist, for TS.
Donald L. Gilbert+7 more
wiley +1 more source
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro+5 more
wiley +1 more source
The Antiviral Activity of Polyphenols
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard+5 more
wiley +1 more source
Nerve cells partially mitigate indomethacin‐induced tight junction dysregulation in neuro‐gut epithelial cell cocultures. Human milk oligosaccharides 2′‐ and 3‐fucosyllactose (2′‐FL and 3‐FL) protect the neuro‐gut epithelial barrier from indomethacin‐induced damage. This protection is stronger in cocultures with higher nerve cell densities.
Xiaochen Chen+3 more
wiley +1 more source
Interstitial Cystitis/Bladder Pain Syndrome in Men
ABSTRACT Aims In April 2025, the Wake Forest Institute for Regenerative Medicine hosted a Global Consensus meeting on interstitial cystitis/bladder pain syndrome (IC/BPS) in Winston‐Salem, NC. The goal of this meeting was to establish attainable targets in phenotyping, diagnosis, and biomarkers for IC/BPS.
Madeline Snipes+5 more
wiley +1 more source
Two Ulcers on the Chin That Developed After Fever: Quiz Case
JEADV Clinical Practice, EarlyView.
Viktor Capiau+3 more
wiley +1 more source
Abstract The literature is inconsistent regarding differences in infection risk between central venous catheter types used for home parenteral nutrition (HPN). Our goal was to determine if significant differences exist in rates of infection and other complications between peripherally inserted central catheters, tunneled central venous catheters, and ...
Theresa A. Fessler+3 more
wiley +1 more source
Pediatric Sharp Foreign Body Aspiration: Revealing Unexpected Risk Factors
Abstract Objective Characterize the demographic and clinical features of pediatric sharp foreign body aspiration (FBA). Study Design Twenty‐four‐year retrospective chart review. Setting Four tertiary‐care centers across four Canadian provinces. Methods A retrospective chart review was conducted on pediatric patients who underwent rigid bronchoscopy for
Alicia Belaiche+6 more
wiley +1 more source