Roles of bile acids in enteric virus replication. [PDF]
Anim Dis, 2021 Bile acids (BAs) are evolutionally conserved molecules synthesized in the liver from cholesterol to facilitating the absorption of fat-soluble nutrients.
Kong F, Saif LJ, Wang Q.
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The Intestinal Microbiome Primes Host Innate Immunity against Enteric Virus Systemic Infection through Type I Interferon. [PDF]
mBio, 2021 While cumulative data indicate that indigenous commensal bacteria can facilitate enteric virus infection, little is known regarding whether intestinal microbes have a protective role in antagonizing enteric systemic infection by modulating host innate ...
Yang XL +6 more
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Gastrointestinal organoid technology advances studies of enteric virus biology. [PDF]
PLoS Pathog, 2020 The historical lack of models recapitulating the complexity of the human intestinal epithelium has hindered studies into many aspects of human enteric virus biology.
Kolawole AO, Wobus CE.
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Next-Generation Porcine Intestinal Organoids: an Apical-Out Organoid Model for Swine Enteric Virus Infection and Immune Response Investigations. [PDF]
J Virol, 2020 Intestinal organoids are a newly developed culture system for investigating pathogen-host interactions. Intestinal organoid models have been widely used since their development, because the results obtained from this type of culture model better ...
Li Y +7 more
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CRISPR-Cas9-Based Technology for Studying Enteric Virus Infection [PDF]
Frontiers in Genome Editing, 2022 Enteric viruses, including numerous viruses that initiate infection in enteric canal, are recognized as important agents that cause wide spectrum of illnesses in humans, depending on the virus type.
Junki Hirano +2 more
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Bacteriophages as indicators of faecal pollution and enteric virus removal. [PDF]
Lett Appl Microbiol, 2017 Bacteriophages are an attractive alternative to faecal indicator bacteria (FIB), particularly as surrogates of enteric virus fate and transport, due to their closer morphological and biological properties.
McMinn BR, Ashbolt NJ, Korajkic A.
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Enteric Virus Diversity Examined by Molecular Methods in Brazilian Poultry Flocks. [PDF]
Vet Sci, 2018 Enteric viruses play an important role in the Brazilian poultry industry due to the economic impact of resulting low yields of broilers, layers, and breeders.
De la Torre DI +3 more
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Sex-Dependent Intestinal Replication of an Enteric Virus. [PDF]
J Virol, 2017 Coxsackievirus is an enteric virus that initiates infection in the gastrointestinal tract before disseminating to peripheral tissues to cause disease, but intestinal factors that influence viral replication are understudied.
Robinson CM, Wang Y, Pfeiffer JK.
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Nanopore sequencing as a revolutionary diagnostic tool for porcine viral enteric disease complexes identifies porcine kobuvirus as an important enteric virus. [PDF]
Sci Rep, 2018 Enteric diseases in swine are often caused by different pathogens and thus metagenomics are a useful tool for diagnostics. The capacities of nanopore sequencing for viral diagnostics were investigated here.
Theuns S +8 more
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A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection. [PDF]
Proc Natl Acad Sci U S A, 2017 Significance Understanding host–enteric virus interactions has been limited by the inability to culture nontransformed small intestinal epithelial cells and to infect animal models with human viruses.
Saxena K +13 more
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