Results 111 to 120 of about 20,208 (266)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

[The sensitivity of enterobacteria to disinfectants].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1994
The presence of variants resistant to disinfectants in the natural populations has been established by original methods and with the use of a complex of indices. The occurrence, levels and spectra of acquired resistance depend on the type of a disinfecting agent and the habitat of bacteria.
A P, Krasil'nikov, E I, Gudkova
openaire   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Colonization of the gut by <i>Klebsiella pneumoniae</i> and its multidrug-resistant strains is well marked in preterm neonates. [PDF]

Front Cell Infect Microbiol
El-Shanqetti EM, Albasri HM, Waznah MS, Morsy FM.   +3 more
europepmc   +1 more source

[Amine decomposition by enterobacteria].

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1975
TOMODA, Tsunesuke, YAMAGUCH, Haruo, KANEDA, Nobuo   +2 more
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Prophage diversity in poultry-associated <i>Salmonella enterica</i> from Ecuador: a case study using an <i>in-silico</i> terminase-based approach. [PDF]

Front Microbiol
Quelal-Madrid F, Armijos CE, Vinueza-Burgos C, Mejía L, Zapata-Mena S.   +4 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Structural characterization of the native oligomerization mode of MvaT proteins in <i>Pseudomonas</i>. [PDF]

Microbiol Spectr
Vasileva D, Suzuki-Minakuchi C, Arakawa T, Moriwaki Y, Yonezawa K, Shimizu N, Fujimoto Z, Terada T, Okada K, Nojiri H.   +9 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source