Results 221 to 230 of about 197,218 (326)

Klebsiella pneumoniae contributes to altered cytotoxicity of thiopurines in vitro: Possible implications of biotransformation and bacterial metabolism

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 18, Page 4281-4298, September 2025.
Abstract Background and purpose Thiopurines are used in paediatric inflammatory bowel disease (IBD), but some patients do not respond. Because the gut microbiota influences drug efficacy and IBD‐patient microbiota presents increased bacterial abundance, we investigated the impact of candidate Enterobacteriaceae on drug cytotoxicity, metabolism and ...
Martina Franzin   +13 more
wiley   +1 more source

Comparison of Carbapenem vs. Amikacin Antimicrobial Therapy for Pediatric Acute Pyelonephritis Caused by Extended-Spectrum Β-Lactamase-Positive Enterobacteriaceae. [PDF]

open access: yesChildren (Basel)
Cura Yayla BC   +8 more
europepmc   +1 more source

Concordance of molecular microbiology and conventional culture techniques for infected diabetic foot ulcer management

open access: yesDiabetic Medicine, Volume 42, Issue 9, September 2025.
Abstract Aim The management of infected diabetic foot ulcers (DFUs) requires balancing the need for timely interventions against the desire for targeted antibiotic therapy, which relies on laboratory results. This study aimed to evaluate concordance between molecular and conventional culture and sensitivity (C&S) methods in identifying bacteria from ...
Angela Oates   +48 more
wiley   +1 more source

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