Results 221 to 230 of about 250,135 (303)

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

open access: yesPortal Hypertension &Cirrhosis, Volume 5, Issue 2, Page 170-188, June 2026.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu   +5 more
wiley   +1 more source

Computational design of a soluble mimic of the outer membrane LPS transport protein LptD suitable for screening of antibiotics

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Lipopolysaccharides (LPS) are the principal chemical component of the outer leaflet of Gram‐negative bacteria and constitute the first barrier of defense against foreign molecules. Inhibition of LPS transport presents a novel concept for antibiotic discovery, and components of the transport bridge are targets of antimicrobial peptides. LptD, a
Wenzhao Dai   +5 more
wiley   +1 more source

Temperature‐Dependent Effects of Laboratory‐Heated Dissolved Organic Matter on Aquatic Microbiome Composition and Nitrogen Cycling Dynamics

open access: yesJournal of Geophysical Research: Biogeosciences, Volume 131, Issue 6, June 2026.
Abstract Wildfires generate partially combusted biomass that mobilizes to aquatic ecosystems as dissolved pyrogenic organic matter (dPyOM) in runoff, where it can impact surface water quality. However, the influence of dPyOM on aquatic microbiome composition, functional gene distribution, and biogeochemical processes remains poorly understood, with ...
Saraf Islam Promi   +3 more
wiley   +1 more source

Comparative Effects of Cigarette and Hookah Smoking on Oral Microbiota Composition and Blood Indices in Young Adult Males

open access: yesFASEB BioAdvances, Volume 8, Issue 6, June 2026.
This study examined 87 healthy young males to compare the effects of cigarette and hookah smoking on oral microbiota and hematological parameters. Cigarette smokers showed the highest oral bacterial load and greater colonization by Candida albicans and Gram‐positive cocci, while hookah smokers also exhibited elevated microbial levels.
Fayez Alghofaili   +8 more
wiley   +1 more source

ESBL-producing and virulent enteric bacteria from goats in Northeastern Brazil. [PDF]

open access: yesVet Res Commun
Silva GV   +7 more
europepmc   +1 more source

Cefdinir binding to a class A β‐lactamase revealed by serial cryo‐crystallography

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 672-682, June 2026.
Serial cryo‐crystallography reveals the structure of the extended‐spectrum β‐lactamase CTX‐M‐14 in complex with the third‐generation cephalosporin antibiotic cefdinir.One of the most common resistance mechanisms against antibiotics employed by Gram‐negative bacteria involves the production of β‐lactamases, resulting in rapid hydrolysis of the ...
Gargi Gore   +4 more
wiley   +1 more source

Interplay of Diet, Heat Stress, and the Microbiome Shapes Health and Escape Behaviour in Amphibian Larvae

open access: yesEnvironmental Microbiology, Volume 28, Issue 6, June 2026.
Diet and temperature jointly shape the gut microbiome and host performance in amphibian larvae. In a multifactorial experiment with Rana temporaria, diet quality, rearing temperature, and heatwave exposure altered microbial communities and predicted metabolic pathways, while host health remained largely stable, suggesting microbiome plasticity and ...
Paula C. Eterovick   +4 more
wiley   +1 more source

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