Results 71 to 80 of about 350,167 (400)

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

Advanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen, Huafeng Geng, Yang Zheng, Hongyang Xie, Rui Qin, Junyang Chen, Cong Ye   +6 more
wiley   +1 more source

Carbapenem Resistance In Enterobacteriaceae [PDF]

Sohag Medical Journal, 2020
Carbapenem resistance is now a public health concern worldwide. Carbapenem is considered the last resort antimicrobial drug used for treatment of hospital care associated infection and community acquired infection that resistant to all other β-lactam drugs. There are a different mechanisms by which bacteria become resistant to carbapenem drug including
Hasnaa Abo-Elwafa, Radwa Mohammed Farag, Hadir Elmahllawy, Laila M. Yousef   +3 more
openaire   +2 more sources

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

Advanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding, Xingfu Bao, Ying Zhao, Lin Bai, Jinming Zhang, Chengjing Xu, Tianyan Chen, Shuang Dai, Yufu Liu, Min Hu, Meng Qin, Zhen Liu   +11 more
wiley   +1 more source

Genome plasticity in Enterobacteriaceae

International Journal of Medical Microbiology, 2000
The comparative analysis of multiple representatives of the genomes of particular species are leading us away from a view of bacterial genomes as static, monolithic structures towards the view that they are relatively variable, fluid structures. This plasticity is mainly the result of the rearrangement of genes within the genome and the acquisition of ...
Werner Brunder, Helge Karch
openaire   +3 more sources

Novel Role of Gut‐Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure

Advanced Science, EarlyView.
Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Lixiao Zhou, Chunsong Wang, Jieying Gao, Xu Wu, Geng Li, Xuejun Jiang, Yinyin Xia, Jun Zhang, Bo Lv, Feng Zhao, Hongyang Zhang, Huifeng Pi, Jingfu Qiu, Shangcheng Xu, Zhen Zou, Chengzhi Chen   +15 more
wiley   +1 more source

Worsening epidemiological situation of carbapenemase-producing Enterobacteriaceae in Europe, assessment by national experts from 37 countries, July 2018

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019
A survey on the epidemiological situation, surveillance and containment activities for carbapenemase-producing Enterobacteriaceae (CPE) was conducted in European countries in 2018. All 37 participating countries reported CPE cases.
A. Brolund, N. Lagerqvist, Sara Byfors, M. Struelens, D. Monnet, B. Albiger, A. Kohlenberg   +6 more
semanticscholar   +1 more source

An Inflammation‐Targeting Engineered Probiotic Escherichia coli Nissle 1917 with High Anti‐TNF‐α Nanobody Secretion Efficacy Alleviates Ulcerative Colitis

Advanced Science, EarlyView.
Ulcerative colitis therapy requires precise drug targeting. This study engineers a probiotic E. coli Nissle 1917 to surface‐display ANXA5, enabling specific binding to phosphatidylserine (PS) exposed on inflamed colonic epithelium for enhanced targeting and colonization.
Siqi Hua, Kaiqiang Li, Pengyou Shang, Lina Liu, Jiayu Pan, Bo Zhu, Zichun Hua   +6 more
wiley   +1 more source

Midgut microbiota of the malaria mosquito vector Anopheles gambiae and Interactions with plasmodium falciparum Infection [PDF]

, 2012
The susceptibility of Anopheles mosquitoes to Plasmodium infections relies on complex interactions between the insect vector and the malaria parasite.
A Chao, A Rani, AK Benson, Alexandra Marie, AM Briones, AM Mendes, Anne Boissière, AV Santos, B Chouaia, C Costantini, C Dale, C Damiani, C Fanello, C Gouveia, C Harris, C Wondji, CA Lowenberger, CB Pumpuni, CB Pumpuni, CD Marsden, CJF Ter Braak, CJF Ter Braak, CM Cirimotich, Dipankar Bachar, E Crotti, E Crotti, E Zaura, Elena A. Levashina, F Armougom, F Simard, FH Collins, G Avgustin, G Elango, G Favia, G Reid, Hamid R. Shahbazkia, II Ivanov, Isabelle Morlais, J Jadin, J Okasen, J Qin, J Rodrigues, JF Petrosino, JM Lindh, K Zouache, KD Vernick, Kenneth D. Vernick, KM Maslowski, KS Hayes, KW Mah, L Gonzalez-Ceron, Luc Abate, LV Hooper, LV Hooper, M Farenhorst, M Kane, Majoline T. Tchioffo, ME Bruno, MK Lawniczak, ML Metzker, ML Sogin, MM Riehle, MO Ndiath, MS Beier, N Buchon, N Windbichler, O Terenius, P Kampfer, Parfait H. Awono-Ambene, PJ Turnbaugh, R Andreotti, R Christen, R Fabre, R Kindt, R Miyata, RE Ley, RE Ley, Richard Christen, RJ Dillon, RJ Dillon, RM Moll, S Compant, S Meister, SA Blandin, Sandrine E. Nsango, SC Straif, SK Kuss, SM Geib, T Stoeck, TL Turner, U Hentschel, VG Martinson, Y Dong, Y Kikuchi, Y Kikuchi   +94 more
core   +5 more sources

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Effects of N-(Alkoxyphenyl)-1-hydroxynaphthalene-2-carboxamides on Intestinal Microbial Communities

Chemistry Proceedings, 2023
The phylum Proteobacteria, more precisely, the family Enterobacteriaceae, has been shown to be a major cause of inflammation in the human microbiome.
Vanina Nikolaeva, Tomas Gonec, Ivan Kushkevych, Josef Jampilek   +3 more
doaj   +1 more source