Results 101 to 110 of about 822 (260)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Presencia de B-lactamasas de espectro extendido en enterobacterias aisladas de casos de infección nosocomial

Ciencia Ergo Sum, 2011
Las enterobacterias son los microorganismos etiologicos mas frecuentemente asociados a las infecciones nosocomiales (in), caracterizandose por su alta resistencia a los antibioticos B-lactamicos, mediada por la produccion de B-lactamasas de Espectro ...
Sergio Pavón Romero, Mayra Zalazar Gómez, Macario Morales Rodríguez, Mercedes Rojas Pedral   +3 more
doaj  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

[Prospective study of the incidence density of multi-resistant microorganisms and Clostridioides difficile during the period 2012- 2019 in the Canary Islands]. [PDF]

Rev Esp Quimioter, 2021
de Arriba-Fernández A, Molina-Cabrillana MJ, Serra-Majem L, García-de Carlos P.   +3 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Combinación de antibióticos carbapenémicos con relebactam sobre enterobacterias productoras de carbapenemasas

Correo Científico Médico
Las enterobacterias productoras de carbapenemasas se han diseminado por todo el mundo y causan infecciones de alta mortalidad y morbilidad. Los antibióticos carbapenémicos se utilizan como último recurso frente a las infecciones graves producidas por ...
Washington Paúl Culqui Molina, Martha Elizabeth Loor Flores, Mónica Viviana Moscoso Silva   +2 more
doaj  

[Pseudocitrobacter anthropi sepsis in a patient with complicated urinary tract infection]. [PDF]

Rev Esp Quimioter, 2021
Cebollada Sánchez R, Lavilla Fernández MJ, Betrán Escartín A, Ortega Larrea D, Torres Sopena L.   +4 more
europepmc   +1 more source