Results 1 to 10 of about 43,020 (182)

ALAS2 Prevents Neonatal Necrotizing Enterocolitis by Improving Ferroptosis in Intestinal Epithelial Cells Through Inhibition of Oxidative Stress. [PDF]

Mediators Inflamm
Neonatal necrotizing enterocolitis (NEC) is an intestinal disease that occurs in the neonatal period. The purpose of this study was to investigate the role of 5′‐aminolevulinate synthase 2 (ALAS2) in NEC‐induced intestinal injury. In a neonatal mouse, NEC model was induced by high‐osmolarity formula and hypoxia‐cold stress, and ALAS2 expression was ...
Hao Z, Han J, Yao T, Zhao Z, Fan W, Jiang Z, Wang Y, Yang X, Xu Z.   +8 more
europepmc   +2 more sources

Necrotizing enterocolitis [PDF]

The Indian Journal of Pediatrics, 2001
Improvement in survival rates of low birth-weight infants particularly in the neonatal intensive care units of India appears to be accompanied by frequent recognition of Necrotizing enterocolitis (NEC) among early survivors. As the philosophy and practice of advanced care for tiny infants becomes more acceptable and affordable in the country, a steady ...
Kulkarni, Anjali, Vigneswaran, R.
openaire   +2 more sources

Nutrition in necrotizing enterocolitis and following intestinal resection [PDF]

, 2020
This review aims to discuss the role of nutrition and feeding practices in necrotizing enterocolitis (NEC), NEC prevention, and its complications, including surgical treatment.
Courtney, Cathleen M, Ou, Jocelyn, Steinberger, Allie E, Tecos, Maria E, Warner, Brad W   +4 more
core   +2 more sources

Necrotizing Enterocolitis [PDF]

New England Journal of Medicine, 2011
William O.
Josef, Neu, W Allan, Walker
openaire   +6 more sources

Necrotizing enterocolitis [PDF]

Archives of Disease in Childhood, 1974
BECAUSE of its probable increased incidence there is need to be aware of the fatal-if untreated-condition called necrotizing enterocolitis. With this in mind the clinical and pathological features of ten infants with the condition are presented. The unreliability of radiological signs in diagnosis is stressed; the primary role of shock is supported and
S F, Calahane, B, Moore
openaire   +3 more sources

Transactivation of EGFR by LPS induces COX-2 expression in enterocytes [PDF]

, 2012
Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal morbidity and mortality in preterm infants. NEC is characterized by an exaggerated inflammatory response to bacterial flora leading to bowel necrosis.
A Grishin, AA Fanaroff, AA Maynard, Anatoly Grishin, AO Fagbemi, AV Grishin, B Dvorak, B Lugo, BB Warner, BJ Stoll, BK Reuter, CE Shin, CL Leaphart, Claus Schneider, CP Sodhi, D Hsu, D. Brent Polk, DH Chung, Henri Ford, JA Clark, Jeffrey Upperman, JL Koff, Jörn-Hendrik Weitkamp, M Fukata, M Fukata, M Petrosyan, MD Halpern, Michael J. Rosen, Michael Kallen, Nathalie Signoret, Noemi Tejera, O Morteau, P Chailler, PJ Miettinen, Poojitha Matta, PW Lin, RR Nair, S Cetin, SC Fitzgibbons, SC Gribar, SC Gribar, SO Guthrie, Steven J. McElroy, Stuart Hobbs, T Jilling, T Yamaoka   +45 more
core   +9 more sources

Current status of laboratory and imaging diagnosis of neonatal necrotizing enterocolitis [PDF]

, 2018
Necrotizing enterocolitis continues to be a devastating disease process for very low birth weight infants in Neonatal Intensive Care Units. The aetiology and pathogenesis of necrotizing enterocolitis are not definitively understood.
Corsello G, D'Angelo G, Falsaperla R, Gitto E, Impellizzeri P, Marseglia L, Montalto AS, Romeo C, Russo T, Salamone I   +9 more
core   +1 more source

Probiotic administration in congenital heart disease: a pilot study. [PDF]

, 2013
ObjectiveTo investigate the impact of probiotic Bifidobacterium longum ssp. infantis on the fecal microbiota and plasma cytokines in neonates with congenital heart disease.Study designSixteen infants with congenital heart disease were randomly assigned ...
Bokulich, NA, Ellis, CL, Elumalai, J, Haapanen, L, Kalanetra, KM, Mills, DA, Mirmiran, M, Raff, G, Rutledge, JC, Schegg, T, Underwood, MA   +10 more
core   +2 more sources

Determining optimal outcome measures in a trial investigating no routine gastric residual volume measurement in critically ill children [PDF]

, 2020
Background Choosing trial outcome measures is important. When outcomes are not clinically relevant or important to parents/patients, trial evidence is less likely to be implemented into practice.
Andrzejewska, Izabela, Arch, Barbara, Beissel, Anne, Deja, Elizabeth, Dorling, Jon, Eccleson, Helen, Gale, Chris, Hickey, Helen, Jones, Ashley P., Latten, Lynne, Pathan, Nazima, Preston, Jenny, Roper, Louise, the Paediatric Intensive Care Society Study Group (PICS-SG), Tume, Lyvonne N., Valla, Frederic V., Woolfall, Kerry   +16 more
core   +2 more sources

Hydrogen Sulfide Donor GYY4137 Acts Through Endothelial Nitric Oxide to Protect Intestine in Murine Models of Necrotizing Enterocolitis and Intestinal Ischemia [PDF]

, 2019
BACKGROUND: Necrotizing enterocolitis (NEC) in premature infants is often a devastating surgical condition with poor outcomes. GYY4137 is a long-acting donor of hydrogen sulfide, a gasotransmitter that is protective against intestinal injury in ...
Drucker, Natalie A., Jensen, Amanda R., Markel, Troy A., Te Winkel, Pieter Jan   +3 more
core   +1 more source