Results 41 to 50 of about 31,899 (267)

Modulation of human immune responses by bovine interleukin-10

open access: yes, 2011
Cytokines can be functionally active across species barriers. Bovine IL-10 has an amino acid sequence identity with human IL-10 of 76.8%. Therefore, the aim of this study was to evaluate whether bovine IL-10 has immunomodulatory activities on human ...
Schoemaker, R.   +27 more
core   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

open access: yesAnimal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen   +7 more
wiley   +1 more source

Assessment of the state of hemodynamic in the area of superior mesenteric artery in newborns with necrotizing enterocolitis

open access: yesНеонатологія, хірургія та перинатальна медицина, 2019
The feasibility and effectiveness of superior mesenteric artery Doppler ultrasonography in the diagnosis of necrotizing enterocolitis and other gastrointestinal pathologies in newborns were evaluated in this article. It was found that with in necrotizing
E.A. Artemenko   +4 more
doaj   +1 more source

Preclinical model of neonatal necrotizing enterocolitis

open access: yes, 2021
The disclosure provides methods of generating a murine model of neonatal necrotizing enterocolitis, whereby the generated murine animal exhibits at least one symptom of neonatal necrotizing enterocolitis.
Maheshwari, Akhil, Krishnan, Mohan Kumar
core  

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul   +7 more
wiley   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga   +20 more
wiley   +1 more source

Expression and Possible Role of Silent Mating Type Information Regulation 2 Homolog 1 in Post-necrotizing Enterocolitis Stricture in vivo and in vitro

open access: yesFrontiers in Pediatrics, 2022
PurposeTo investigate the expression and possible role of Sirtuin1 or Silent mating–type information regulation 2 homolog-1 (SIRT1) in post-necrotizing enterocolitis stricture.Materials and MethodsThe expression characteristics of SIRT1 and TGF-β1 in ...
Rui Chen   +6 more
doaj   +1 more source

Stricture after Necrotizing Enterocolitis

open access: yes, 1984
To the Editor: Kliegman and Fanaroff indicate that intestinal strictures are present in as many as 10 per cent of patients after necrotizing enterocolitis (April 26 issue).1 In contrast, my colleagues and I reviewed our data retrospectively and found a ...
Bouton, Jean Marie   +4 more
core   +1 more source

Percutaneous Deployment of the Sinus‐SuperFlex‐DS Stent for Hybrid Stage I Palliation in Neonates Weighing ≤ 2.5 kg: A Multicenter Study

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Hybrid stage I palliation (HS1P) has developed as an alternative to the Norwood stage I palliation for neonates with hypoplastic left heart and related left‐sided obstructive lesions. HS1P is currently used in various clinical settings, such as single ventricle palliation, bridge to decision, bridge to biventricular repair, or ...
Johanna Hummel   +8 more
wiley   +1 more source

Burden and its associated factors of neonatal necrotizing enter colitis among neonates admitted in neonatal intensive care unit in Ethiopia. A systematic review and meta-analysis

open access: yesInternational Journal of Africa Nursing Sciences
Neonatal Necrotizing enterocolitis is the most critical and recurrent gastrointestinal disorder in neonatal intensive care units. Although the overall mortality extends to 50 % related to necrotizing enterocolitis, it can approach 100 % with perforation,
Demewoz Kefale   +8 more
doaj   +1 more source

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